Publications by authors named "Mei-Shan Zhao"
Front Microbiol
April 2023
Article Synopsis
- Gut microbiota may play a role in the development of clear cell renal cell carcinoma (ccRCC), but the specific mechanisms are still unclear.
- A study comparing fecal samples from 30 ccRCC patients and 30 healthy controls found significant differences in the overall gut microbiota structures, although the overall diversity was similar.
- Specific bacterial species were identified as more or less abundant in ccRCC patients, and changes in serum taurine levels and macrophage-related gene expression may indicate potential risk factors for the disease.
Transl Androl Urol
August 2022
Article Synopsis
- Ferroptosis-related genes (FRGs) are crucial for understanding the survival and prognosis of prostate cancer patients, leading to the development of a predictive model to assess overall and disease-free survival based on immune cell infiltration characteristics.
- A comprehensive analysis involving 268 FRGs revealed differentially expressed genes using the TCGA database, employing various bioinformatics methods including Cox regression to create prognostic models linked to clinicopathological features.
- The established models indicated that advanced cancer stages (T3-4) and N0 stages showed better predicted survival rates; additionally, distinct patterns of immune cell infiltration associated with ferroptosis were identified, highlighting the role of specific immune cells in high- and low-risk groups.
