Synopsis of recent research by authors named "Mei-Ling Tien"
- Mei-Ling Tien's research focuses on the effects of mechanical ventilation on diaphragm function, particularly how high tidal volume mechanical ventilation influences cellular signaling pathways.
- In her 2011 study, Tien explores the impact of prolonged mechanical ventilation on the diaphragm, highlighting the increased activity in important protein pathways such as protein kinase B and c-Jun NH2-terminal kinase.
- The findings suggest that mechanical ventilation may induce inflammatory responses and contribute to diaphragmatic injury, which can complicate the weaning process for patients after extended ventilation.