Publications by authors named "Mei-Juan Hao"
Article Synopsis
- Immunotherapy for esophageal squamous cell carcinoma (ESCC) shows varying effectiveness, and recent research highlights the role of circular RNAs (circRNAs) in the tumor microenvironment.
- A comprehensive network of immune-related circRNA, microRNA, and mRNA was constructed, comprising 16 circRNAs, 13 microRNAs, and 1,560 mRNAs, revealing the competing endogenous RNA (ceRNA) dynamics in ESCC.
- Key findings included the identification of cancer-associated fibroblast (CAF) modules linked to immune scores, with specific collagen family genes showing elevated expression and potential as targets for ESCC treatment, contributing to more personalized clinical approaches.
Oesophageal squamous cell carcinoma (ESCC) is a common malignant tumour of the gastrointestinal tract. Early detection and access to appropriate treatment are crucial for the long-term survival of patients. However, limited diagnostic and monitoring methods are available for identifying early stage ESCC.
View Article and Find Full Text PDF