Influences of different sedatives on gastric antrum contraction in patients with acute brain injury.

Background: Patients with acute brain injury (ABI) often exhibit gastrointestinal motility disorder and the administration of sedatives may exacerbate the gastrointestinal dysfunction. This study aims to evaluate the influences of different sedatives on gastric antrum contraction in patients with acute brain injury (ABI).

Methods: A prospective observational study was performed in 37 adult ICU patients with ABI, and 18 adult healthy volunteers were recruited as normal controls.

Phytohormones involved in vascular cambium activity in woods: current progress and future challenges.

Vascular cambium is the continuation of meristem activity at the top of plants, which promotes lateral growth of plants. The vascular cambium evolved as an adaptation for secondary growth, initially in early seed plants, and became more refined in the evolution of gymnosperms and angiosperms. In angiosperms, it is crucial for plant growth and wood formation.

Drug Interaction of SGLT2Is and ARNI on Acute Kidney Injury: A Real-world Pharmacovigilance Analysis Through the FAERS.

Sodium-glucose cotransporter 2 inhibitors (SGLT2Is) and angiotensin receptor-neprilysin inhibitor (ARNI) may cause potential renal damage, the combined impact of SGLT2Is and ARNI on acute kidney injury (AKI) remains unclear. This pharmacovigilance study conducted a disproportionality analysis using reports from the FAERS database. The reporting odds ratio (ROR) was used as an estimate for detecting AKI signal.

Peroxiredoxin 4 Ameliorates T-2 Toxin-Induced Growth Retardation in GH3 Cells by Inhibiting Oxidative Stress and Apoptosis.

T-2 toxin, a highly toxic type A trichothecene, is a secondary fungal metabolite produced by various Fusarium species. The consumption of food and feed contaminated with T-2 toxin is a major factor contributing to growth retardation, posing significant risks to both human and animal health. However, the specific targets and mechanisms that mitigate T-2 toxin-induced growth retardation remain unclear.

Insights into the performance and mechanism of a reinforced lignocellulosic sorbent fabricated from sawdust biomass for multi-tasking application in enrofloxacin removal and monitoring.

Natural lignocellulose-based materials have numerous strengths such as abundance, cheap price and biodegradability, which indicates a brilliant prospect for environmental protection. This work aimed to design an efficient sorbent (NaSS-PSD) by pine sawdust (PSD) for the surveillance and management of enrofloxacin (ENR). In the study, sodium styrenesulfonate (NaSS) was chosen as an effective monomer to ameliorate the performance of PSD by graft copolymerization.

Physicians and hospital pharmacists' knowledge, attitudes, and practices towards polypharmacy in older patients with chronic diseases.

This web-based cross-sectional study aimed to evaluate the knowledge, attitudes, and practices of physicians and hospital pharmacists towards polypharmacy in older adult patients with chronic diseases in China. This study enrolled 374 physicians and pharmacists (270 females, 92 physicians) in 20 Chinese provinces between December 2022 and March 2023. The knowledge, attitude, and practice scores were 12.

Effect of sodium hypochlorite and EDTA pretreatment on the resin infiltration efficacy and acid resistance of enamel white spot lesions: an in vitro study.

Background: This in vitro study aimed to evaluate the effect of sodium hypochlorite (NaOCl) and ethylene diamine tetraacetic acid (EDTA) as pretreatments on the resin infiltration efficacy and acid resistance of enamel white spot lesions (WSLs).

Methods: Enamel blocks prepared from the buccal surfaces of sound human premolars were placed in a demineralisation solution for 3 days to establish artificial enamel WSLs. All the blocks with WSLs were randomly divided into four groups (n = 40 per group): RI (Control): resin infiltration only.

Thermal Decomposition of Core-Shell-Structured RDX@AlH, HMX@AlH, and CL-20@AlH Nanoparticles: Reactive Molecular Dynamics Simulations.

The reactive molecular dynamics method was employed to examine the thermal decomposition process of aluminized hydride (AlH) containing explosive nanoparticles with a core-shell structure under high temperature. The core was composed of the explosives RDX, HMX, and CL-20, while the shell was composed of AlH. It was demonstrated that the CL-20@AlH NPs decomposed at a faster rate than the other NPs, and elevated temperatures could accelerate the initial decomposition of the explosive molecules.

Screening of active components of melastoma dodecandrum lour. against diabetic osteoporosis using cell membrane chromatography-mass spectrometry.

Background: Melastoma dodecandrum Lour. (MD), a traditional botanical drug known for its hypoglycemic, antioxidant, and anti-inflammatory properties, is commonly used to treat diabetes, osteoarthritis, and osteoporosis. However, its specific active components against diabetic osteoporosis remain unclear.

A hydrogen passivation strategy for the electrocatalytic chlorine evolution reaction on metal-organic frameworks: a theoretical insight.

The chlorine evolution reaction (CER) is a crucial solution for treating chlorine-containing wastewater, a type of wastewater generated during the chemical production process. Electrocatalysts applied are mainly dimensionally stable anodes (DSAs) such as precious metals and their oxides. In order to reduce the amounts of rare metals in the catalysts and to improve the catalytic performance, a hydrogen-passivated transition metal site strategy based on a metal-organic framework, TM(THT) (TM = Mn, Fe, Co, Ni, Tc, Ru, Rh, Pd, Re, Os, Ir, Pt), was proposed to force the CER to proceed at the sulfur (S) site.

Tooth-Binding Graphene Quantum Dots Silver Nanocomposites for Prevention of Dental Caries.

Objective: The objectives of this study were to develop a tooth-binding graphene quantum dots silver nanocomposites (ALN-GQDs-Ag) and evaluate their antibacterial, mineralising, and discolouring properties for the prevention of dental caries.

Methods: In this study, ALN-GQDs-Ag were developed by synthesising nano silver (Ag) with graphene quantum dots (GQDs) and functionalised GQDs with alendronate (ALN). ALN-GQDs-Ag were characterised by transmission electron microscopy (TEM), zeta potential analysis, X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR), and Raman spectroscopy.

The Chromosome-Scale Genome of Magnolia sieboldii K. Koch Provides Insight Into the Evolutionary Position of Magnoliids and Seed Germination.

Magnolia sieboldii K. Koch (M. sieboldii) stands as an elegant tree species within the Magnoliaceae family, esteemed for its exquisite beauty, cultural significance and economic advantages.

On efficient expanding training datasets of breast tumor ultrasound segmentation model.

Automatic segmentation of breast tumor ultrasound images can provide doctors with objective and efficient references for lesions and regions of interest. Both dataset optimization and model structure optimization are crucial for achieving optimal image segmentation performance, and it can be challenging to satisfy the clinical needs solely through model structure enhancements in the context of insufficient breast tumor ultrasound datasets for model training. While significant research has focused on enhancing the architecture of deep learning models to improve tumor segmentation performance, there is a relative paucity of work dedicated to dataset augmentation.

In Vitro Models Used in Cariology Mineralisation Research-A Review of the Literature.

Background: Dental caries remains a significant global health problem. One of the fundamental mechanisms underlying the development and progression of dental caries is the dynamic process of demineralisation/remineralisation. In vitro models have played a critical role in advancing our understanding of this process and identifying potential interventions to prevent or arrest dental caries.