Publications by authors named "Mei Lin Zheng"
Article Synopsis
- A newly isolated bacterium, strain 2021, from contaminated soil has shown the capability to degrade fluorene while being highly resistant to arsenic.
- Strain 2021 demonstrated optimal performance in degrading fluorene in the presence of arsenic, suggesting that arsenic may actually promote its growth and degradation abilities.
- The study highlights the genetic responses involved in arsenic resistance and hydrocarbon degradation, indicating the potential of strain 2021 in bioremediation of environments impacted by arsenic and polycyclic aromatic hydrocarbons.
The metabolic mechanisms for imidazolidine oxidation of imidacloprid (IMI) by cytochrome P450 3A4 (CYP3A4) have been investigated using quantum mechanical/molecular mechanical (QM/MM) calculations. The binding mode of CYP3A4 with IMI is examined by molecular docking in collaboration with molecular dynamics (MD) simulations. The results show that there are six amino acid residues, involving Arg192, Phe195, Ile349, Ala285, Phe284 and Phe88, closely distributed around the IMI.
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