Publications by authors named "Mei Koyama"
A measles outbreak occurred in Japan in February 2024 due to a measles virus variant that was imported from central Asian countries with three mismatches at the PCR reverse primer (MVN1213R) annealing site. To examine and improve the impact of real-time PCR effectiveness for detecting this variant, we compared the sensitivity of real-time PCR between MVN1213R and a modified primer using control RNAs, clinical isolates, and clinical specimens. The median difference in the cycle threshold value was 2.
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- * PCF cases in Osaka dropped significantly from 2020 to 2022, but there was a notable rise in cases in 2023, with HAdV-B3 becoming the most frequently detected type.
- * Genetic analysis revealed new variants of HAdV-B3 were circulating in 2023, suggesting that children became more susceptible to the virus due to a lack of exposure during the previous years of the pandemic.