Publications by authors named "Mei Ito"

Environmental microorganisms possess enzymes that can digest macromolecules such as agarose into smaller molecules that can be utilized for growth. These enzymes could be valuable for the effective utilization of global resources. However, since most of the microorganisms on Earth remain uncultured, there is significant untapped enzymatic potential in nature.

View Article and Find Full Text PDF

We report the complete genomic sequences of two agarolytic species strains, STUT-A11 and STUT-A16, isolated from the red algae . Genomic annotations revealed that both strains harbor four β-agarases, α-neoagarooligosaccharide hydrolase, and agarolytic β-galactosidase, which support efficient agarose catabolism.

View Article and Find Full Text PDF
Article Synopsis
  • Researchers identified a unique set of gene clusters involved in producing macrolide natural products from fungi, featuring a specific enzyme known as GPI-EPT.
  • By expressing two of these gene clusters in different systems, they generated new types of macrolides that included modified phospholipid components.
  • This study is groundbreaking as it shows how GPI-EPT homologues contribute to the biosynthesis of these complex natural products, revealing new genetic sources for similar fungal compounds.
View Article and Find Full Text PDF