Publications by authors named "Mei Huan Chang"
Article Synopsis
- - The study analyzed over 373,000 single-cell transcriptomes from colorectal cancer patients to better understand the diversity of epithelial cells, revealing distinct genetic and gene expression differences among malignant cells.
- - Two new intrinsic subtypes, iCMS2 and iCMS3, were identified, with iCMS3 linked to worse outcomes and encompassing both microsatellite unstable (MSI-H) and some microsatellite-stable (MSS) cancers.
- - The research proposes a refined 'IMF' classification that incorporates intrinsic epithelial subtype, microsatellite instability status, and fibrosis, leading to five distinct subtypes of colorectal cancer.
Background: Single-incision laparoscopic surgery (SILS) is a recent development of minimally invasive surgery for colorectal disease. The literature comparing it against conventional laparoscopic colectomy remains limited.
Methods: A retrospective case-cohort study compared the benefits and outcomes of SILS right hemicolectomy (SRH) with those of conventional laparoscopic right hemicolectomy (LRH).