Publications by authors named "Mehruba A Parris"
Article Synopsis
- Thallium is a toxic metal, and this case details a young man who intentionally ingested elemental thallium purchased online, leading to dangerously high serum and urine thallium levels.
- The patient was treated with Prussian blue, a medication that binds to thallium, after having the ingested metal fragment removed via colonoscopy.
- Despite initial severe thallium levels that typically indicate fatal exposure, the patient showed no signs of toxicity after 23 days in the hospital, highlighting a need for more research on the effects of elemental thallium versus thallium salts.
Background: Experts recommend using the lowest effective dose of naloxone to balance the reversal of opioid-induced respiratory depression and avoid precipitated opioid withdrawal, however, there is no established dosing standards within the emergency department (ED).
Objectives: The aim of this review was to determine current naloxone dosing practice in the ED and their association with adverse events.
Methods: We conducted a systematic review by searching PubMed, Cochrane, Embase, and EBSCO from 2000-2021.
Approximately 30% of poison exposures reported to centers each year are either referred to or initiated within a health care facility. Among these exposures, undifferentiated poisoned patients are among the most challenging cases faced in the emergency department. Airway, breathing, circulation (ABCs) is central to the management of unknown poisoned patient.
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- Acute chloroquine and hydroxychloroquine toxicity leads to serious cardiovascular issues and electrolyte imbalances, resulting in potentially fatal dysrhythmias.
- This toxicity is particularly concerning given the drugs' narrow therapeutic range and their increased usage, especially during the COVID-19 pandemic.
- Emergency department management focuses on stabilizing patients through decontamination, correcting electrolyte imbalances, and providing cardiac support to reduce morbidity and mortality.
Left Ventricular Regional Wall Motion Abnormality in the Setting of Acute Loperamide Overdose.
Clin Pract Cases Emerg Med
August 2019
Loperamide is an inexpensive, over-the-counter antidiarrheal agent with emerging reports of overdose due to its opioid properties. Although it is considered by many patients to be safe, cardiotoxicity has been reported, prompting the United States Food and Drug Administration to release a warning regarding the arrhythmogenic potential of loperamide. We present a case of a 32-year-old male presenting in acute loperamide overdose and subsequent cardiac dysrhythmia with focal wall motion abnormalities on echocardiogram.
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