Publications by authors named "Mehrotra A"

Unlike most other Medicare fee schedules, the Medicare Physician Fee Schedule does not include an automatic inflation update. We describe the history of Physician Fee Schedule update systems and present paradigms for evaluating the merits of adding an inflation-based adjustment factor to the schedule's updating formulas. We adopt an incentive paradigm, which emphasizes how access to care and the consolidation of health care facilities are affected by fees.

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  • The study examines the clinical and surgical management of aneurysmal bone cysts (ABCs) in the temporal bone, analyzing six case studies treated between 2017 and 2024 at a tertiary care institution.
  • Key findings indicate that the average patient age was 27.5 years, with symptoms like scalp swelling and hearing impairment, and successful surgeries resulted in no recurrences during a follow-up period.
  • The research concludes that complete surgical removal is the best treatment for temporal bone ABCs, stressing the importance of the tumor's stage and the extent of resection in determining patient outcomes.
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Inflammatory myofibroblastic tumor (IMT) is a rare, benign lesion of uncertain etiology, predominantly affecting soft tissues such as the lungs, with spinal involvement being exceedingly rare. We present the case of a 10-year-old male with a year-long history of low back pain, constipation, and difficulty in urination. MRI revealed an intradural extramedullary lesion at L5-S1, initially suspected to be a schwannoma or neurofibroma.

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Climate change poses a significant threat to the sustainability of livestock production systems in developing countries, particularly impacting small ruminants like goats, which are highly susceptible to heat stress. This stressor not only reduces productivity but also undermines economic viability. This study aimed to delve into the molecular mechanisms underlying heat stress tolerance in goats by conducting a comprehensive transcriptome analysis of heat-tolerant (HT, n = 4) and heat-susceptible (HS, n = 6) Jamunapari goats.

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Objective: The authors sought to understand patient experiences with group teletherapy to inform improvements in service delivery.

Methods: From December 2022 to October 2023, semistructured interviews were conducted with 20 adults with depression or bipolar disorder who had received outpatient group teletherapy in the past 2 years. A rapid thematic analysis was conducted by using a matrix to identify patterns and synthesize data.

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  • Keyhole surgical approaches for aneurysm clipping are becoming popular, yet there's limited research comparing them or guiding new surgeons in their use.
  • A study involving 24 patients revealed that the mini-pterional approach (MPA) was the most common method, with some complications occurring more often in the supraorbital techniques.
  • Overall, results indicate that with careful patient selection, MPA and lateral supraorbital approaches lead to excellent outcomes, although the supraorbital keyhole approach (SOKHA) presents a steeper learning curve.
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  • * MCAO animals exhibited increased levels of inflammatory markers and reduced locomotor activity, while WS pre-supplementation reduced those inflammatory markers and improved neurotransmitter levels like GABA and catecholamines.
  • * The findings indicate that WS can effectively mitigate neuroinflammation, neurochemical changes, and motor impairments associated with IRI in the MCAO model of ischemic stroke, highlighting its potential therapeutic benefits.
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Background: Proximal femur fracture surgeries have become increasingly prevalent, presenting unique challenges for postoperative pain management due to patient demographics and comorbidities. Erector spinae plane block (ESPB) has emerged as a relatively safe alternative to paravertebral block (PVB). Our aim was to compare ultrasound-guided continuous ESPB with continuous PVB for postoperative analgesia in patients undergoing proximal femur surgeries under spinal anesthesia.

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Terminal myelocystocele (TMC) is a rare form of spinal dysraphism which arises due to aberration in the secondary neurulation process involving the caudal cell mass. Terminal myelocystocele has been defined by Pang et al. based on essential and non-essential features.

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  • The study aims to identify demographic and clinical groups experiencing racial and gender disparities in emergency department admissions, focusing on White and African-American adults.* -
  • Analysis involved nearly 94,000 patients and highlighted that African-American women were notably less likely to be admitted than White men across various subpopulations, while African-American men and White women also faced lower admission odds in certain age and insurance categories.* -
  • The research suggests that young patients and those with low comorbidity scores or Medicaid/self-pay insurance are particularly vulnerable to these disparities, indicating a need for targeted interventions in these demographics.*
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  • The study focuses on understanding the causes and effects of invasive fungal rhinosinusitis that impacts the skull base, examining data from 79 patients over a 5-year period at a specialized hospital.
  • Key findings revealed that a significant portion (65.8%) of cases involved skull base rhino-orbitocerebral mucormycosis (ROCM), with a notable overlap with COVID-19 and diabetes mellitus among affected patients.
  • The research highlights that the pterygopalatine fossa was the most commonly affected area, with important neurovascular structures like the pterygopalatine ganglion also frequently involved, stressing the importance of monitoring invasive fungal infections post-COVID-19.
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  • - The study investigates the feasibility of measuring the extent of resection (EOR) and residual tumor volume (RTV) in glioma patients using MRI in resource-limited healthcare settings, finding it feasible in only 31% of cases.
  • - It shows that while volumetric analysis, which is more precise than surgeons’ estimates, does not correlate significantly with patient survival, factors like tumor grade and postoperative functional status are more impactful for survival outcomes.
  • - The research highlights logistical challenges in implementing routine volumetric assessments in developing countries, suggesting a need for better resource allocation in neurosurgical practices.
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  • Congenital spondylolisthesis is a condition in which there is a defect in the spine, often affecting children and characterized by varying degrees of spinal misalignment mostly at the L5-S1 region.
  • A study analyzed 22 patients over three years, finding that most had high-grade listhesis and reported significant improvements in pain and disability after surgical intervention.
  • The research concluded that while surgery is challenging, it can effectively alleviate symptoms, with non-reductive fixation being a viable option in certain cases to prevent complications during surgery.
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Aneurysms of the distal anterior cerebral artery (DACA) are rare but surgically challenging. Despite a known therapeutic implication of the aneurysm location on the DACA territory, the literature is unclear about its clinical and prognostic significance. Our surgical experience over the last 5 years was reviewed to compare the clinical, operative, and outcome characteristics between aneurysms located below the mid portion of the genu of the corpus callosum (called proximal aneurysms) to those distal to this point (called distal aneurysms).

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Policy Points The reinstitution of pre-COVID-19 pandemic licensure regulations has impeded interstate telehealth. This has disproportionately impacted patients who live near a state border; geographically mobile patients, such as college students; and patients with rare diseases who may need care from a specialist outside their state. Several promising and feasible reforms are available, at both state and federal levels, to facilitate interstate telehealth.

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Importance: The incidence of hospital encounters for acute myocardial infarction (AMI) decreased sharply early in the COVID-19 pandemic and has not returned to prepandemic levels. There has been an ongoing debate about what mechanism may underlie this decline, including patients avoiding the hospital for treatment, excess mortality from COVID-19 among patients who would otherwise have had an AMI, a reduction in the incidence or severity of AMIs due to pandemic-related changes in behavior, or a preexisting temporal trend of lower AMI incidence.

Objective: To describe drivers of changing incidence in AMI hospital encounters during the COVID-19 pandemic.

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Background: Artificial intelligence (AI) applications in health care have been effective in many areas of medicine, but they are often trained for a single task using labelled data, making deployment and generalisability challenging. How well a general-purpose AI language model performs diagnosis and triage relative to physicians and laypeople is not well understood.

Methods: We compared the predictive accuracy of Generative Pre-trained Transformer 3 (GPT-3)'s diagnostic and triage ability for 48 validated synthetic case vignettes (<50 words; sixth-grade reading level or below) of both common (eg, viral illness) and severe (eg, heart attack) conditions to a nationally representative sample of 5000 lay people from the USA who could use the internet to find the correct options and 21 practising physicians at Harvard Medical School.

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Background/objective: Visual impairment affects 55%-80% of medial sphenoid wing meningiomas (mSWMs) patients, making optic nerve decompression a critical surgical goal. Complete resection often leads to better visual outcomes. However, involvement of critical neurovascular structures increases postoperative morbidity and mortality, with vascular injury reported in 18%-20% of cases.

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