Association analysis between genomic variants within advanced glycation end product specific receptor () gene and risk of breast cancer in Iranian women.

The advanced glycation end product specific receptor () gene codes for a cell surface receptor which is one of the immunoglobulin superfamily members. This gene has a number of single nucleotide polymorphisms (SNPs) whose variants are associated with altered function of the encoded protein. In the current project, we examined association between rs184003 and rs1800625 SNPs and susceptibility to breast cancer in an Iranian population.

Association study of Retinoic Acid Related Orphan Receptor A (RORA) gene and risk of prostate disorders.

Purpose: Prostate cancer (PCa) and benign prostate hyperplasia (BPH) are two prevalent disorders among men with considerable mortality and morbidity. Several association studies have been conducted in different populations to find genetic loci linked with these disorders. Retinoic acid-receptor-related orphan receptor alpha (RORA) codes for a transcription factor which regulates expression of several cancer-related genes.

Frequency of viral infections and environmental factors in multiple sclerosis.

Objectives: Multiple sclerosis (MS) is a complicated disease which occurs due to relationship between genes and environmental factors that causes tissue damage by autoimmune mechanisms.We investigated and illustrated the hypotheses correlated to the evidence of several putative environmental risk factors for MS onset and progression in this part of Iran.

Materials And Methods: Univariate logistic regression was used to detect the effects of environmental factors on the risk of MS.