Publications by authors named "Mehrdad Sadeghi Haj"

Article Synopsis
  • HTLV-1 is associated with serious diseases like adult T-cell leukemia/lymphoma and tropical spastic paraparesis, and understanding its prevalence in areas like Alborz province, Iran, is crucial.
  • The study focused on the genetic analysis of the virus, particularly the highly conserved long terminal repeat (LTR) region and the Tax oncoprotein, to understand its phylogenetic relationships.
  • Among about 15,000 blood donors, only 19 tested positive for HTLV-1, showing a 0.13% positivity rate, with the virus identified as subtype A; while mutations were present, they did not significantly impact the virus's functions or virulence.
View Article and Find Full Text PDF

Background And Objectives: Adenoviral keratoconjunctivitis is an extremely frequent ophthalmological disease caused by various serological subtypes of human adenovirus (HAdV) worldwide. Adenoviruses serotypes 8, 11, 19, 37 frequently cause epidemic keratoconjunctivitis (EKC). This study was conducted to evaluate the frequency of adenovirus serotypes in patients with EKC in Ahvaz, Iran.

View Article and Find Full Text PDF
Article Synopsis
  • Acute respiratory infections (ARIs) are a major health issue globally, with particular concern for viral factors like Enteroviruses (EVs) and Human Rhinoviruses (HRVs), which have been newly classified under EVs due to their shared family, Picornaviridae.
  • A study conducted with samples from 100 hospitalized patients in Ahvaz, Iran, from December 2012 to November 2013 used Semi-Nested PCR to detect HRVs and EVs, revealing 19% were HRV positive and only 3% were EV positive.
  • Results indicated that HRVs were most prevalent in autumn, with specific strains identified as HRV-A9, HRV-A49, and HRV-B14
View Article and Find Full Text PDF

Background: Highly active antiretroviral therapy (HAART) has been commonly used for HIV treatment. Its main drawbacks like drug resistance and side effects raised researcher's interest to find new approaches for its treatment. Trimethyl chitosan is one of the drug carriers which has been introduced recently.

View Article and Find Full Text PDF

Objectives: Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS) with unknown etiology. Various genetics and environmental factors contribute to the pathogenesis of the disease. The interleukin-7 receptor alpha chain (IL-7Ra) was identified as the first non-major histocompatibility complex (non-MHC) MS susceptibility locus.

View Article and Find Full Text PDF

Background: Health care workers are at high risk of acquiring hepatitis B virus (HBV) infection through occupational exposure to blood or body fluids. Thus, the assessment of anti-HBs status after immunization is very important.

Objectives: This study aimed to evaluate the measurement of HBsAb titer and specific gamma interferon response among the vaccinated health care workers in Golestan Hospital, Ahvaz, Iran.

View Article and Find Full Text PDF