Publications by authors named "Mehrdad Azarmi"
Article Synopsis
- - Early-life nutrition, particularly the inclusion of prebiotics like galacto-oligosaccharides and human milk oligosaccharides, can improve vaccine responses in infants, as shown in a study with mice.
- - Mice on a specific diet (combination of GOS/lcFOS and HMOS) exhibited stronger immune responses, evidenced by increased ear swelling (a measure of delayed-type hypersensitivity) and higher levels of specific antibodies (IgG1).
- - The diet enhanced the activation of immune cells, particularly memory B lymphocytes and Th1 cells, indicating that incorporating these prebiotics into infant formulas could lead to better immune development and vaccine efficacy in infants.
Neurolisteriosis is an infectious disease of the central nervous system (CNS) with a high mortality rate caused by Listeria monocytogenes. The CNS disorders suffer from inadequacy of drugs accessibility. An experimental in vivo model of neurolisteriosis was developed by oral administration of the bacteria in Wistar rats.
View Article and Find Full Text PDFThe blood-brain barrier (BBB) has a pivotal role in maintaining brain homeostasis. It robustly protects the brain parenchyma against the invasion of irrelevant substances, which may interrupt its critical function. From a pharmaceutical point of view, such a barrier may cause central nervous system (CNS) disorders refractory by restricting the therapeutics from accessing to their target sites in cerebral parenchyma.
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