A novel intelligent thermoresponsive-magnetic molecularly imprinted polymer (TMMIP) nanocomposite based on N-isopropylacrylamide (NIPAM) & FeO was designed for the controlled & sustained release of Curcumin (CUR) with the ability to response external stimulus. The TMMIP nanocomposite was prepared using acryl functionalized β-cyclodextrin (β-CD) and NIPAM as functional monomers and CUR as target molecule. The recognition cavities which caused by host-guest interactions had direct influence to enhanced drug loading and sustained release of CUR.
View Article and Find Full Text PDFA sensitive and selective molecularly imprinted polymer (MIP) for the determination of diphenylamine (DPA) was developed based on host-guest interactions of a cyclodextrin-based polymer which possesses an inherent affinity for the target. The proposed GO@MIP has been prepared using the graphene oxide (GO) sheets as surface of polymerization, DPA as target molecule, β-cyclodextrin (β-CD) and acrylamide (AM) as functional monomers, azobisisobutyronitrile (AIBN) as initiator and N, N methylene bisacrylamide (MBAm) as crosslinker which denoted as GO@MIP nanocomposite. The MIP sites were formed by the inclusion complex through interaction of DPA and β-CD, followed by extraction of target.
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