Publications by authors named "Mehran Goharian"

As the COVID-19 spread continues to challenge the societal and professional norms, radiotherapy around the globe is pushed into an unprecedented transformation. We will discuss how clinical physics has transformed to ascertain safety and quality standards across four facilities around the world through diversity of action, innovation, and scientific flexibility.

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Purpose: To report the 5-year biochemical relapse-free survival (BRFS), overall survival (OS), and long-term toxicity outcomes of patients treated with low-dose-rate (LDR) brachytherapy as monotherapy for low- to intermediate-risk prostate cancer.

Material And Methods: Between 2004 and 2011, 371 patients were treated with LDR brachytherapy as monotherapy. Of these, 102 patients (27%) underwent transurethral resection of the prostate (TURP) prior to implantation.

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During the recommissioning of a Philips RT-250 kilovoltage X-ray unit, unexpected output variations with tube head rotation (cross-plane) and tube head tilt (in-plane) were observed. The measured output showed an increase of up to 7.3% relative to the neutral position (0? in-plane and 0? cross-plane) over the possible range of angles of in-plane rotation for 75 kVp (half-value layer, HVL = 1.

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This paper describes the design of a multi-frequency Electrical impedance tomography (EIT) system, which provides a flexible mechanism for addressing up to 48 electrodes for imaging conductivity and permittivity distributions. A waveform generator based on a digital signal processor is used to produce sinusoidal waveforms with the ability to select frequencies in the range of 0.1-125 kHz.

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Electrical impedance tomography, EIT, is an imaging modality in which the internal conductivity distribution of an object is reconstructed based on voltage measurements on the boundary. This reconstruction problem is a nonlinear and ill-posed inverse problem, which requires regularization to ensure a stable solution. Most popular regularization approaches enforce smoothness in the inverse solution.

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This paper presents a trust-region implementation for image reconstruction of conductivity changes in electrical impedance tomography. A dogleg trust-region algorithm is applied in different cases to detect abnormalities. The dogleg algorithm approximates a Levenberg-Marquardt step within the trust region of the model function with a quadratic model.

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