A comprehensive study on methylene blue removal via polymer and protein nanoparticle adsorbents.

Water pollution, particularly from industrial contaminants such as dyes, is a significant global concern. Various technologies, including nanoscale materials, are employed for water and wastewater treatment. Among these, adsorption process as an effective method due to its simplicity, cost-effectiveness, and reliability.

Removal of the nalidixic acid antibiotic from aqueous solutions using bovine serum albumin nanoparticles.

The presence of antibiotic pollutants in water and wastewater can cause significant risks to the environment in different aspects. Therefore, antibiotics need to be removed from water. This study investigates the adsorption of nalidixic acid (NA), a common antibiotic, using bovine serum albumin nanoparticles (BSA NPs).

Multi-layer Bundling as a New Approach for Determining Multi-scale Correlations Within a High-Dimensional Dataset.

The growing complexity of biological data has spurred the development of innovative computational techniques to extract meaningful information and uncover hidden patterns within vast datasets. Biological networks, such as gene regulatory networks and protein-protein interaction networks, hold critical insights into biological features' connections and functions. Integrating and analyzing high-dimensional data, particularly in gene expression studies, stands prominent among the challenges in deciphering these networks.

Conversion of spikers to bursters in pituitary cell networks: Is it better to disperse for maximum exposure or circle the wagons?

The endocrine cells of the pituitary gland are electrically active, and in vivo they form small networks where the bidirectional cell-cell coupling is through gap junctions. Numerous studies of dispersed pituitary cells have shown that typical behaviors are tonic spiking and bursting, the latter being more effective at evoking secretion. In this article, we use mathematical modeling to examine the dynamics of small networks of spiking and bursting pituitary cells.

Network Properties of Electrically Coupled Bursting Pituitary Cells.

The endocrine cells of the anterior pituitary gland are electrically active when stimulated or, in some cases, when not inhibited. The activity pattern thought to be most effective in releasing hormones is bursting, which consists of depolarization with small spikes that are much longer than single spikes. Although a majority of the research on cellular activity patterns has been performed on dispersed cells, the environment is characterized by networks of coupled cells of the same type, at least in the case of somatotrophs and lactotrophs.

Chronic stress facilitates bursting electrical activity in pituitary corticotrophs.

Coordination of an appropriate stress response is dependent upon anterior pituitary corticotroph excitability in response to hypothalamic secretagogues and glucocorticoid negative feedback. A key determinant of corticotroph excitability is large conductance calcium- and voltage-activated (BK) potassium channels that are critical for promoting corticotrophin-releasing hormone (CRH)-induced bursting that enhances adrenocorticotrophic hormone secretion. Previous studies revealed hypothalamic-pituitary-adrenal axis hyperexcitability following chronic stress (CS) is partly a function of increased corticotroph output.

Fast-slow analysis of a stochastic mechanism for electrical bursting.

Electrical bursting oscillations in neurons and endocrine cells are activity patterns that facilitate the secretion of neurotransmitters and hormones and have been the focus of study for several decades. Mathematical modeling has been an extremely useful tool in this effort, and the use of fast-slow analysis has made it possible to understand bursting from a dynamic perspective and to make testable predictions about changes in system parameters or the cellular environment. It is typically the case that the electrical impulses that occur during the active phase of a burst are due to stable limit cycles in the fast subsystem of equations or, in the case of so-called "pseudo-plateau bursting," canards that are induced by a folded node singularity.

Phantom bursting may underlie electrical bursting in single pancreatic β-cells.

Insulin is secreted by pancreatic β-cellsthat are electrically coupled into micro-organs called islets of Langerhans. The secretion is due to the influx of Caions that accompany electrical impulses, which are clustered into bursts. So-called "medium bursting" occurs in many β-cellsin intact islets, while in other islets the β-cellsexhibit "slow bursting", with a much longer period.

Dataset for adsorptive removal of tetracycline (TC) from aqueous solution via natural light weight expanded clay aggregate (LECA) and LECA coated with manganese oxide nanoparticles in the presence of HO.

In this data article, natural (NL) and manganese oxide-modified LECA (MML) adsorbents were applied for adsorptive removal of Tetracycline (TC) from aqueous solution. The used adsorbents was characterized using fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD) and X-ray fluorescence spectroscopy (XRF). The chemical analysis of XRF data revealed increased chemical composition of Mn as MnO to 8.

Administration of Intravenous Zoledronic Acid Every 3 Months vs. Annually in β-thalassemia Patients with Low Bone Mineral Density: a Retrospective Comparison of Efficacy.

Introduction: The benefit of annual administration of zoledronic acid in the management of thalassemia-associated osteoporosis is unknown.

Aim: The aims of this study were to evaluate the efficacy of treatment with two different dosing regimens of IV zoledronic acid (annually versus every 3 months) for increasing low bone mineral density (BMD) in patients with osteoporosis associated with β-thalassemia as annually and 3-monthly on bone density in patients.

Materials And Methods: This retrospective, single-center study analyzed patients' clinical records and bone density measurements.

The Short Term Effects of Shock-Wave Therapy for Tennis Elbow: a Clinical Trial Study.

Background: Tennis elbow is one of the most often diagnosed pathology of the upper extremity and different treatments have been suggested for this disease, so this study was to investigate the effects of extracorporeal shock wave therapy in Tennis elbow treatment.

Materials And Methods: We design a before and after clinical trial study (registry number: IRCT2012072610405N1) and investigated 40 patients with tennis elbow disease. All patients received 2000 pulses extracorporeal shock wave by piezoelectric device (WOLF Company) daily for one-week.

Evaluation the Relationship Between Thyroid Nodule Size with Malignancy and Accuracy of Fine Needle Aspiration Biopsy (FNAB).

Introduction: Some studies have shown largest thyroid nodule size, especially ≥4cm that can predict malignancy and reduce fine needle aspiration biopsy (FNAB) accuracy. Therefore, this study is designed to evaluate relationship between thyroid nodule sizes with malignancy and its effect on FNBA accuracy.

Materials And Methods: a retrospective analytical study design aims to investigate all patients with thyroid nodules who referred to surgery department of Imam-Khomeini Hospital of Mazandaran University of Medical Sciences in Sari from 20 March 2008 to 22 March 2014.

Pilonidal Sinus Operations Performed Under Local Anesthesia versus the General Anesthesia: Clinical Trial Study.

Backgrounds: Various methods were defined to prepare patients for the pilonidal sinus surgery including local, spinal, and general anesthesia. But there is no powerful evidence to differ these procedures. Therefore, in the current study, we compared local and general anesthesia in the pilonidal sinus surgery.

A Survey of Severity and Distribution of Musculoskeletal Pain in Multiple Sclerosis Patients; a Cross-Sectional Study.

Background: Pain, a common phenomenon in multiple sclerosis (MS) patients, is associated with many symptoms and problems.

Aim: To investigation severity and distribution of musculoskeletal pain in MS patients.

Methods: In this cross-sectional study, 115 members of the Mazandaran MS Association with confirmed MS were randomly selected to participate in the study.

Evaluations of erectile dysfunction before and after on-pump coronary artery bypass graft surgery.

Background: Erectile dysfunction (ED) is common in cardiovascular disease (CVD) and indicates a complication of coronary artery bypass graft surgery (CABG). This study was designed to evaluate the status of erectile dysfunction in patients with CAD before and after CABG surgery.

Methods: We designed a prospective cohort study on male patients candidates for elective on-pump CABG between June 2006 to October 2012 in 3 hospitals in Sari, Iran (Fatemeh Zahra, Shafa and Nime-Shaban Hospitals).

Efficiency of non-ionic surfactants - EDTA for treating TPH and heavy metals from contaminated soil.

Introduction of fuel hydrocarbons and inorganic compounds (heavy metals) into the soil, resulting in a change of the soil quality, which is likely to affect use of the soil or endangering public health and ground water. This study aimed to determine a series of parameters to remediation of TPH and heavy metals contaminated soil by non-ionic surfactants- chelating agents washing process. In this experimental study, the effects of soil washing time, agitation speed, concentration of surfactant, chelating agent and pH on the removal efficiency were studied.

Clinical management and outcomes of papillary, follicular and medullary thyroid cancer surgery.

The clinical characteristics, pathological subtypes and patients' survival in 40 patients with thyroid carcinoma between March 2007 and March 2012 were evaluated. This study included 33 (82.5 %) females and seven (17.