Publications by authors named "Mehran Asad Ayoubi"
Article Synopsis
- Rituximab (RTX) is being used off-label for systemic lupus erythematosus (SLE) with non-renal symptoms, but there is limited trial evidence on its effectiveness.
- A study analyzed 20 reports involving 59 patients with a high clinical response rate of 90% after RTX treatment, with a relapse rate of one-third within 9.5 months.
- RTX seems to be particularly effective for patients with psychosis, those without mood disorders, and those with a disease duration of less than 3 years, although there were some safety concerns with a 33% infection rate during treatment.
For a hydrogel based on a zwitterionic dendritic surfactant, we report an apparently unprecedented reversible temperature-induced gel-to-gel phase transition below the melting point of its alkyl chains, where the supramolecular self-assembly of surfactant molecules underwent a dramatic transformation from low-temperature surfactant bilayers to high-temperature entangled surfactant worm-like micelles.
View Article and Find Full Text PDFThe release of double-stranded DNA from its interpolyelectrolyte complex with positively charged poly(allylamine hydrochloride) via exchange reaction with added polyanion, poly(sodium styrenesulfonate), is directly observed by fluorescence microscopy. It is shown that the pathways of DNA release depend essentially on the amount of added low-molecular-weight salt. At low salt content, the DNA release proceeds via the formation of an intermediate "beads-on-string" structure, whereas at high salt content the release goes directly from globule to coil states without any intermediate structures.
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