Ongoing or re-emerging subjective insomnia symptoms after full/partial remission or recovery of major depressive disorder mainly with the selective serotonin reuptake inhibitors and risk of relapse or recurrence: a 52-week follow-up study.

Background: Many patients who remit fully/partially or recover from an episode of major depression continue to suffer from sleep problems, mainly insomnia. Our study assesses the frequency and types of ongoing or re-emerging subjective insomnia symptoms and their relationship to subsequent depressive relapse or recurrence in a group of full/partial remitters or recoverers.

Method: Sixty patients, 18 to 65 years of age, with current MDD defined using DSM-IV-TR criteria were participated in the study.

[Delayed sleep phase type sleep disorder and chronotherapy].

Delayed sleep phase type sleep disorder is a circadian rhythm disorder that results in symptoms of sleep-onset insomnia and difficulty awakening at a desired time. Patients with delayed sleep phase-type sleep disorder can be treated with chronotherapy, light therapy, vitamin B12, or melatonin. Chronotherapy is a behavioral technique in which sleep time is systematically delayed.

[Psychopharmacological treatment and quality of life in obsessive compulsive disorder].

Objective: Obsessive compulsive disorder (OCD) is an illness that considerably influences the family, academic, occupational and social functioning of patients. In this study, we aimed to investigate the impact of psychopharmacological treatment on quality of life in patients with OCD.

Method: Using the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Hamilton Depression Rating Scale (HDRS) and the World Health Organization Quality of Life Measurement Instrument Short Form, Turkish Version (WHOQOL-Bref TR) we assessed 53 patients who met the DSM-IV criteria for OCD to establish baseline values.

[Therapeutic response to plasmapheresis in four cases with obsessive-compulsive disorder and tic disorder triggered by streptococcal infections].

The acronym PANDAS (pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections) has been assigned to a subgroup of patients experiencing pediatric onset obsessive-compulsive symptoms and tics as a result of autoimmune response to group A beta-hemolytic streptococcal infection. It has been hypothesized that an immune process initiated by infection affects the basal ganglia and causes neuropsychiatric symptoms. In cases with severe neuropsychiatric symptoms, the use of treatment strategies that interrupt the autoimmune process responsible for the pathogenesis of PANDAS, such as therapeutic plasmapheresis or intravenous immunoglobulin, has been proposed.

Mood changes after sleep deprivation in morningness-eveningness chronotypes in healthy individuals.

Inconsistent results have been found in the studies evaluating the effect of both total and partial sleep deprivation (SD) on mood in healthy subjects and a few variables have been analyzed as possible predictors. In the present study, we examined whether circadian preference modifies the effect of SD on mood changes in healthy subjects. Sample consisted of 60 healthy volunteers (including 30 morningness and 30 eveningness subjects).

Factors associated with major depressive disorder occurring after the onset of obsessive-compulsive disorder.

Background: We aimed to investigate the correlates of major depressive disorder (MDD) occurring after the onset of obsessive-compulsive disorder (OCD).

Methods: Forty-three OCD patients who developed MDD after the onset of OCD (OCD-MDD group) and 67 OCD patients without MDD (non-MDD, NMDD group) were compared with regard to sociodemographic characteristics, clinical history, symptom severity, types of obsessions and compulsions, insight degree, comorbid axis I and axis II diagnosis and quality-of-life level.

Results: The OCD-MDD group scored significantly higher on measures of obsessions, compulsions and depression severity than did the NMDD.

[The correlates of healthcare seeking behavior in obsessive-compulsive disorder: a multidimensional approach].

Obsessive-compulsive disorder (OCD) is a chronic, distressing, and disabling illness that influences the family, academic, occupational, and social functioning of patients. One of the 10 leading causes of disability worldwide is OCD; however, despite the considerable distress and disability associated with the disorder and the availability of treatment options, many OCD sufferers usually are not inclined to seek healthcare. The factors that may be central to healthcare seek behavior in OCD has scarcely been described in the literature.

A discrimination based on autogenous versus reactive obsessions in obsessive-compulsive disorder and related clinical manifestations.

Introduction: Although putative subtypes of obsessive-compulsive disorder (OCD) have been gradually more recognized, there is no generally accepted subtype discrimination. It has been suggested that autogenous and reactive obsessions stem from different cognitive process. This study aimed to assess existence of gender, age at onset of illness, and comorbidity differences in OCD patients suffering from autogenous and reactive obsessions.

[The assessment of obsessive-compulsive symptoms: the reliability and validity of the Padua inventory in a Turkish population].

Objective: We examined the reliability and validity of the 60-and 41-item versions of the Padua Inventory (PI and PI-R) which were developed to assess the frequency and severity of obsessive-compulsive symptoms, in a Turkish population.

Method: The sample consisted of 43 OCD patients, 30 non-OCD patients with other anxiety disorders, 30 nonobsessional depressed patients, 76 healthy adults, and 181 undergraduate students. We investigated internal consistency, test-retest reliability, and factor structure, concurrent and discriminant validity.

Nightmares and serum cholesterol level: a preliminary report.

Objective: To examine whether there is a relation between nightmares and serum lipid levels.

Methods: Fifteen subjects who met DSM-IV criteria for the diagnosis of nightmare disorder and 15 healthy control subjects participated in the study. We used an enzymatic colorimetric method for cholesterol and triglyceride determination.

Nightmares and terminal insomnia in depressed patients with and without melancholic features.

To investigate the relationship between nightmares and melancholic features (MF) in depression, we compared depressed patients with and without MF (n=82 and n=75, respectively) regarding the presence of nightmares. Nightmares were significantly more frequent in patients with MF. Depressed mood in the morning may be related to negative dream content.

Serum lipid concentrations in obsessive-compulsive disorder patients with and without panic attacks.

Objective: To examine serum lipid levels in patients with obsessive-compulsive disorder (OCD) and to test whether panic symptoms affect lipid concentrations in OCD patients.

Methods: We assessed 33 OCD patients and 33 healthy control subjects matched for sex and age.

Results: OCD patients had higher low-density lipoprotein, very-low-density lipoprotein, and tryglyceride levels, but lower high-density lipoprotein levels, than normal control subjects.

[The reliability and validity of the White Bear Suppression Inventory].

Objective: The White Bear Suppression Inventory (WBSI) is a self-report questionnaire measuring tendency to suppress unwanted intrusive thoughts. The aim of this study was to examine the reliability and validity of the WBSI in a Turkish sample.

Method: Thirty patients who were diagnosed with obsessive-compulsive disorder (OCD) according to DSM-IV criteria and 47 healthy subjects were included in the study.

Serum lipid levels in patients with dissociative disorder.

Objective: There may be an association between a low serum cholesterol level and dissociative disorders.

Method: The subjects of the study were 16 patients with dissociative disorder and 16 normal comparison subjects (two men and 14 women in each group). Total cholesterol, triglyceride, high-density lipoprotein, low-density lipoprotein, and very low density lipoprotein levels were compared.

Clinical importance of nightmare disorder in patients with dissociative disorders.

In the present study the prevalence of nightmare disorder (ND) was examined in patients with dissociative disorders (DD), and comparison was made between those with ND and those without nightmares in terms of clinical characteristics. The 30 patients with DD (5 male and 25 female) were recruited over 12 months in the Yüzüncü Yil University Research Hospital Department of Psychiatry. The subjects were diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders (4th edn) criteria for ND.

Nightmares and dissociative experiences: the key role of childhood traumatic events.

In order to examine the co-occurrence of nightmares with dissociative experiences in the adolescent population and to demonstrate the impact of childhood traumatic events in this association, 292 undergraduate students were interviewed for childhood traumatic events. The Van Dream Anxiety Scale (VDAS) and Dissociative Experiences Scale (DES) were also administered to the subjects. For nightmares a 7.