Publications by authors named "Mehmet Tughan Kiziltug"
Article Synopsis
- The study aims to explore the impact of 2.4 GHz Wi-Fi exposure on brain cell composition, specifically focusing on microRNA and fatty acid profiles in rats.
- Sixteen Wistar Albino rats were split into two groups: one exposed to continuous Wi-Fi radiation for a year and another kept without exposure as a control group.
- Results showed that long-term Wi-Fi exposure increased certain microRNA and fatty acids in the brain, suggesting potential health risks linked to ongoing Wi-Fi use.
Purpose: We aimed to examine the expression levels of the genes encoding adenomatous polyposis coli (APC) 1, APC-2, Dickkopf related protein (DKK)-1, DKK-3, secreted frizzled-related protein (SFRP)-2, SFRP-4, and SFRP-5, which play roles in the Wnt signaling pathway, in lung adenocarcinoma and adjacent normal lung tissues and to evaluate their relationships with clinicopathologic factors.
Materials And Methods: The expression levels of genes in formalin-fixed paraffin-embedded samples of tumor tissue and adjacent intact lung tissue from 57 patients who underwent surgery for lung adenocarcinoma between 2011 and 2018 were determined by real-time PCR analysis.
Results: The expression levels of the DKK-1 in tumor tissue, especially in stage I-II tumor tissue, were significantly suppressed compared to those in normal tissue (p < 0.
Background: We aimed at exploring biological functions of differentially expressed miRNAs during carcinogenesis, to identify miRNAs dysegulations involved in DNA repair mechanisms, and to evaluate potential of miRNAs as prognostic and diagnostic biomarkers for early lung adenocarcinomas (LAC).
Methods: We obtained 21 LAC and paired adjacent normal formalin-fixed, paraffinembedded lung tissues from patients who underwent curative resection for stage I LAC. We compared expression levels of eight miRNAs involved in the DNA repair mechanism between LAC and adjacent tissues.