Publications by authors named "Mehmet M Uzel"

Article Synopsis
  • The study developed a method using deep neural networks (DNNs) to automatically detect and classify epiretinal membranes (ERMs) in OCT scans based on their size.
  • The dataset consisted of 11,061 OCT images, which were analyzed, graded, and divided into training, validation, and test sets, yielding high performance in detection accuracy across different ERM sizes, particularly challenging for small ERMs.
  • Saliency maps were created to visually indicate ERMs within the scans, even in the presence of other retinal features, suggesting potential applications for improved screening and decision-support systems in ophthalmology.
View Article and Find Full Text PDF

Background: This study aims to assess pediatric patients with Open Globe Injury (OGI) using the Modified Pediatric Ocular Trauma Score (MPOTS) and to investigate the correlation between Neutrophil-to-Lymphocyte ratio (NLR) and Platelet-to-Lympho-cyte ratio (PLR) parameters with the prognosis determined by MPOTS.

Methods: In this retrospective study, we included pediatric patients with OGI. Recorded data encompassed demographic details, injury type, duration from injury to surgery, complete ophthalmological examinations, initial and final visual acuities, anterior segment and fundus findings, and NLR and PLR values.

View Article and Find Full Text PDF

Purpose: To investigate the relationship between digital screen time and the development and progression of myopia during the 2019 coronavirus disease (COVID-19) pandemic.

Methods: Children aged 7-18 years who had regular refractive measurement follow-ups before and after the COVID-19 pandemic were included in the study. They were divided into two groups according to their initial refractive status, emmetropic and myopic.

View Article and Find Full Text PDF

Purpose: To analyse the clinical and morphological characteristics of eyes with idiopathic epiretinal membrane (iERM) and foveal herniation (FH).

Methods: Clinical findings and OCT features of patients with iERM and FH were retrospectively analysed. Primary outcome were changes of the best-corrected-visual-acuity (BCVA) and OCT features from baseline to the last visit.

View Article and Find Full Text PDF

Clinical Relevance: Knowledge of work-related eye trauma in the construction and manufacturing industries will facilitate planning of policies and practices to protect against such occurrences.

Background: The aim of this study was to compare demographic, epidemiological, and clinical characteristics of work-related eye trauma in workers in the construction and manufacturing industries.

Methods: Medical board disability reports of subjects who experienced work-related eye trauma were investigated in this retrospective comparative study.

View Article and Find Full Text PDF

Purpose: To determine the prognostic characteristics of optical coherence tomography (OCT) parameters by evaluating diabetic macular edema (DME) patients with early dexamethasone (DEX) shift after three doses of intravitreal ranibizumab (RNB) injection.

Methods: Fifty-four eyes of 34 patients who had DEX implant after three doses of RNB were included in this retrospective study. Early DEX shift includes patients who received direct DEX implant replacement after three doses of RNB load.

View Article and Find Full Text PDF

Purpose: To investigate the usefulness of systemic inflammatory markers [i.e., white blood cell and platelet counts, mean platelet volume, and their ratios] as diagnostic markers of the pathogenesis of diabetic macular edema.

View Article and Find Full Text PDF

Purpose: To investigate the effect of topical pilocarpine on topical cycloplegia and on the results of refractive surgery.

Methods: The study included 100 eyes of 100 patients who underwent laser-assisted in situ keratomileusis. Group 1 comprised patients who wanted to undergo surgery on the same day after cycloplegic examination and were applied with 2% pilocarpine hydrochloride; group 2 comprised patients whose pupils spontaneously went into the natural position.

View Article and Find Full Text PDF

Objectives: The aim of this study was to define the optimal cutoff value of the neutrophil/lymphocyte ratio (NLR) to predict severe grades of diabetic retinopathy (DR).

Methods: A total of 40 patients with proliferative DR (PDR) and 40 patients with severe non-proliferative DR (NPDR) were included this prospective, case control study, and 35 age- and sex-matched healthy subjects were recruited as a control group. White blood cell (WBC) count mean values and ratios were compared between the groups.

View Article and Find Full Text PDF

Purpose: To compare the efficacy of Samfilcon A and Lotrafilcon B bandage contact lenses after photorefractive keratectomy (PRK).

Methods: In this study, patients with bilateral PRK were assigned for the fitting of Lotrafilcon B lens and Samfilcon A lens. The patients were examined on the day of surgery and on postoperative days 1, 2 and 3.

View Article and Find Full Text PDF

This study was conducted to reveal the role of systemic low-grade inflammation by calculating the Neutrophil/Lymphocyte Ratio (NLR) in Vitreomacular Traction Syndrome (VMTS) of different etiologies. A retrospective examination was made of the medical records at a tertiary referral hospital. The study included 31 patients with diabetic VMTS, 27 patients with idiopathic VMTS, and 35 healthy subjects as the control group.

View Article and Find Full Text PDF

Optic disk pit, one of the optic disk cavitary anomalies, is generally congenital and unilateral and occurs equally in males and females. Optic disk pit maculopathy is characterized by intraretinal and subretinal fluid at the macula, causing visual deterioration. The origin of the macular fluid and the mechanism of transition to the subretinal space in optic disk pit maculopathy pathophysiology are not yet fully understood.

View Article and Find Full Text PDF

Purpose: To assess the impact of symptom duration on the recurrence of rhegmatogenous retinal detachment (RRD) and to determine the threshold symptom duration for recurrence.

Patient And Methods: In this non-comparative, observational case series, a retrospective evaluation was made of the records of patients with RRD at baseline and during the postoperative follow-up period, in respect of postoperative anatomic outcome, prognostic factors for recurrent retinal detachment and the cutoff value of symptom duration.

Results: Recurrent retinal detachment was detected in 33 (17.

View Article and Find Full Text PDF

Purpose: To evaluate the effect of accelerated corneal crosslinking on corneal biomechanics with an ocular response analyzer in patients with progressive keratoconus.

Methods: In this retrospective study, 50 eyes of 45 patients with progressive keratoconus who underwent accelerated corneal crosslinking were evaluated with ocular response analyzer waveform parameters before and one year after corneal crosslinking. Paired two-tailed Student's t-test was performed to compare the parameters before vs.

View Article and Find Full Text PDF

Sildenafil is one of the most commonly used drugs for sexual dysfunction or to increase libido, and it regulates endothelial nitric oxide synthase enzyme via selective phosphodiesterase-V inhibition. Sildenafil can be easily obtained without a medical indication or prescription yet it is not considered as a completely safe medication. Hemoptysis and hemorrhagic stroke are some important adverse effects of sildenafil.

View Article and Find Full Text PDF

Objectives: To investigate the postoperative changes in the anterior segment parameters by Scheimpflug imaging method in patients undergoing trabeculectomy surgery.

Methods: This prospective study included 38 phakic eyes of 38 patients with primary open-angle glaucoma who underwent trabeculectomy. Anterior chamber angle (ACA), anterior chamber depth (ACD), anterior chamber volume (ACV), and central corneal thickness (CCT) of the eyes were measured by performing Scheimpflug imaging in preoperative (baseline) and postoperative periods (1st week and 1st, 3rd, and 6th months after the surgery).

View Article and Find Full Text PDF

Purpose: To assess the effect of posterior capsular opacification (PCO) and Neodymium-doped:Yttrium Aluminium Garnet (Nd:YAG) laser capsulotomy on tilt and decentration of intraocular lens (IOL) at vertical and horizontal meridians.

Methods: The study included 64 eyes of 64 patients. IOL decentration and tilt were measured using a Scheimpflug camera before and 1 month after Nd:YAG capsulotomy.

View Article and Find Full Text PDF

Purpose: We aimed to investigate the effect of trabeculectomy on serum brain-derived neurotrophic factor (BDNF) levels. Our secondary goal was to compare serum and aqueous humor (AH) BDNF levels in primary open-angle glaucoma (POAG) and control subjects.

Methods: This prospective, cross-sectional study consists of 20 eyes of with advanced-stage POAG who had trabeculectomy and 19 eyes of age- and sex-matched control healthy subjects who had cataract surgery.

View Article and Find Full Text PDF

Purpose: To investigate the corneal densitometry in subclinical keratoconus with normal elevation and pachymetric parameters.

Methods: Patients with clinical keratoconus in one eye and subclinical keratoconus in the fellow eye were identified. The study group was selected from patients with subclinical keratoconus who showed normal results from topographic and Belin-Ambrósio Enhanced Ectasia Display III (BAD) analysis (Kmean <47.

View Article and Find Full Text PDF

Purpose: To evaluate the anterior segment biometric parameters of non-accommodative and accommodative refractive accommodative esotropia (RAE).

Methods: Eighty-one eyes of 81 patients were included in this prospective, case-control study. The patients were divided into three groups as follows: the RAE group (n = 31), the hypermetropia group (n = 25), and the emmetropia group (n = 25).

View Article and Find Full Text PDF

Purpose: To assess the decentration and angle of tilt of the intraocular lens (IOL) according to the intravitreal tamponade types used in combined phacoemulsification and vitreoretinal surgery.

Methods: This prospective and randomized clinical study involved 73 eyes of 69 patients who underwent combined vitreoretinal surgery. Eyes with intravitreal tamponades formed the study group and eyes without intravitreal tamponades formed the control group.

View Article and Find Full Text PDF

Purpose: To assess the compliance with contact lens (CL) use among ophthalmologists and other health professionals, and to identify the main noncompliant behaviors.

Methods: A cross-sectional, comparative study was designed for soft CL wearers. Twenty-five ophthalmologists, 24 medical doctors other than ophthalmologists, 20 nurses (health professionals), and 52 lay people (members of the public) subjects were included in the interview.

View Article and Find Full Text PDF

Purpose: To investigate the effect of Helicobacter pylori (H. pylori) infection on choroidal thickness (CT) and retinal nerve fiber layer thickness (RNFLT).

Methods: The study included 25 patients with H.

View Article and Find Full Text PDF

Purpose: To assess the decentration and tilt of one-piece foldable acrylic intraocular lens following two different intraocular lens implantation techniques.

Methods: This prospective, randomized clinical study conducted on 102 eyes of 91 patients who underwent cataract surgery between September 2015 and May 2016 at Ulucanlar Eye Training and Research Hospital, Ankara, Turkey. Intraocular lens implantations were performed with the help of an ophthalmic viscosurgical device or a hydroimplantation technique during surgery.

View Article and Find Full Text PDF