Publications by authors named "Mehmet Firat"

Hawthorn plant is used among people due to its cardiovascular, anti-inflammatory, and antihistamine properties. But no scientific study has been done about (Mill.) M.

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This study aims to identify trends and hot topics in breeding value to support researchers in finding new directions for future research in that area. The data of this study consist of 7072 academic studies on breeding value in the Web of Science database. Network visualizations and in-depth bibliometric analysis were performed on cited references, authors, countries, institutions, journals, and keywords through CiteSpace.

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The importance of L. species, being used in traditional medicine, in the scientific world is increasing day by day. species are plants that have been used in the treatment of many diseases for a long time and have healing properties.

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Neuroblastoma is the most common solid tumor in children. New treatment approaches are needed because of the harmful side effects and costs of the methods used in the treatment of neuroblastoma. Medicinal and aromatic plants are important for new treatment approaches due to their minimal side effects and economic advantages.

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This article details the ESAFORM Benchmark 2021. The deep drawing cup of a 1 mm thick, AA 6016-T4 sheet with a strong cube texture was simulated by 11 teams relying on phenomenological or crystal plasticity approaches, using commercial or self-developed Finite Element (FE) codes, with solid, continuum or classical shell elements and different contact models. The material characterization (tensile tests, biaxial tensile tests, monotonic and reverse shear tests, EBSD measurements) and the cup forming steps were performed with care (redundancy of measurements).

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Article Synopsis
  • HMG-CoA reductase is a crucial enzyme for cholesterol production and a key target for treating high cholesterol levels.
  • The study evaluated the inhibitory effects of extracts from Vahl. roots and aerial parts, with the root extract showing significant inhibition at 71.97% when tested at 100 µg/mL.
  • Further analysis led to isolating 10 known compounds, with 7-acetoxyhorminone demonstrating the strongest inhibition (84.15%) and effective binding to the enzyme's active site via molecular docking studies.
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The essential oil, aroma, and fatty acid compositions of Salvia cerino-pruinosa var. cerino-pruinosa, S. cerino-pruinosa var.

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: The aim of this study is the synthesis of nanosilver particles (AgNPs) from Agnew. (Geraniaceae) and evaluation of the antimicrobial and the cytotoxic potential of AgNPs. : The synthesized AgNPs were evaluated for antimicrobial and anticancer efficacy using the minimum inhibition concentration method and MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium bromide) assay.

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Being traditionally utilized mainly as appetizers and herbal teas as well as used to ease abdominal pains, colds and gastrointestinal issues, the genus Salvia L. has gained significant consideration owing to its remarkable phytochemicals and industrial importance. The present study aimed to develop and validate an LC-MS/MS method for the qualitative and quantitative investigation of 19 fingerprint phytochemicals in six endemic Salvia species.

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Public use of Salvia species and their importance in the scientific world is continually increasing. It is known that this use and the importance of Salvia species are mostly due to the terpenoid compounds that they contain. In this context, the terpenoid-steroid-flavonoid contents of extracts of six endemic Salvia (S.

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Gundelia species are known as "Kenger-kereng dikeni" in Anatolia, and their aerial parts are consumed as food. Also, roots and seeds (disseminules) of the Gundelia species are used to prepare gum and coffee. The chemical contents of ethanol and hexane extracts of disseminules of 17 Gundelia species, 13 of them are endemic, were studied using LC/MS/MS and GC/MS.

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Allium species are widely consumed as food all over the world. The phenolic profile of ethanol extracts of aerial parts and roots of 12 Allium species, collected from five different Eastern Anatolia regions, were studied using LC-MS/MS. In vitro antioxidant, anticholinesterase, cytotoxic and antimicrobial activities were also tested.

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In the present study, a GC-MS method used for quantitative screening of 26 compounds (sclareolide, sclareol, ferruginol, cryptanol, 6,7-dehydroroyleanone, suginal, 9,10-dihydro-7,8-dimethyl-2-(1-methylethyl) phenanthren-3-ol, sugiol, inuroyleanone, 12-demethylmulticauline, 7α-hydroxy-β-sitosterol, stigmasterol, sitosterol, salvigenin, sinensetin, α-amyrin, lupeol, lupenone, 3-acetyl lupeol, 1α,21α-dihydroxy-2,3-(1'1'-dimethyl-dioxymethylene) urs-9(11),12-dien, uvaol, betulin, pyxinol, lup-(20),29-ene-2α-hydroxy-3β-acetate, betulin 3β, 28β-diacetate, 21α-hydroxy,2α,3β-diacetoxy urs-9(11),12-dien) specific to Turkish Salvia species was developed and validated. According to the GC-MS analysis results, Salvia hypargeia Fisch. & C.

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Background: Almost 90% of cerebral thromboembolism cases are caused by atherosclerosis. Craniocervical atherosclerosis is often observed at the carotid bifurcation and is responsible for 20%-30% of all stroke cases. The course of atherosclerotic carotid artery stenosis varies depending on the grade of stenosis and characteristics of the plaque.

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In this study, the branch, leaves, flowers, roots and mixed parts of different nine species were analyzed for their trace element contents by using ICP-MS. The samples were digested by concentrated nitric acid and hydrogen peroxide in a microwave by ICP-MS before the analysis. The accuracy and precision of the method was evaluated by CRM 1573a Tomato Leaves.

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In the present study, the essential oil and aroma compositions of Nepeta heliotropifolia (NH) and N. congesta subsp. cryptantha (NC) were determined by gas chromatography-mass spectrometry (GC-MS) and gas chromatography-flame ionization detector (GC/FID), and their phenolic compounds by liquid chromatography-tandem mass spectrometry (LC-MS/MS).

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Context: The natural products derived from plants are the important sources that can be used for breast cancer treatment. Salvia species and their derived products were recommended as potential antitumor substances.

Aim: The potential cytotoxic and genotoxic effects of Salvia kronenburgii have been investigated on breast cancer cell lines, MCF-7 and MDA-MB-231.

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This study aims to use the partograph among Turkish women to (a) assess birth curves, (b) define the phase duration of labour, and (c) identify the factors that affect labour. This study was conducted with 496 women and features a retrospective descriptive analysis and a cross-sectional design. The mean duration for the active phase was 5.

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The pollen morphology of Fenzl. and Agnew. from the family Geraniaceae was examined under light microscopy and scanning electron microscopy.

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Purpose: The purpose of this study was to test the reliability and validity of the Turkish version of the Critical Care Family Needs Inventory-Emergency Department (CCFNI-ED) in Turkey.

Methods: This study used a cross-sectional survey design. The questionnaire was administered to 400 family members of patients with a critical illness in an emergency department.

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(Asteraceae) is described as a new species from Hakkâri, Turkey. The new species is a part of the sect. (Cardueae) and similar to , from which it differs in morphological characters such as leaves, involucre, phyllaries, corolla, achens and pollen morphology.

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This study aims at characterizing the asymptotic behavior of genomic prediction R2 as the size of the reference population increases for common or rare QTL alleles through simulations. Haplotypes derived from whole-genome sequence of 85 Caucasian individuals from the 1,000 Genomes Project were used to simulate random mating in a population of 10,000 individuals for at least 100 generations to create the LD structure in humans for a large number of individuals. To reduce computational demands, only SNPs within a 0.

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species have various uses in folk medicine as traditional remedies, and several of them have been screened for their biological activity, including anticancer. Agnew () is traditionally used for its anthelminthic activity. However, little is known about its biological activity or its effect on cancer cells.

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Escherichia coli is the most common pathogen isolated from both nosocomial and community acquired urinary tract infections. Although there are many studies from different centers concerning the antibiotic susceptibility of E.coli isolates in Turkey, the studies are quite few about class 1 and class 2 integron cassettes in clinical E.

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