Publications by authors named "Mehmet Fatih Atak"

Mycosis fungoides (MF) is the most prevalent type of cutaneous T cell lymphomas. Studies on the prognosis of MF are limited, and no research exists on the potential of artificial intelligence to predict MF prognosis. This study aimed to compare the predictive capabilities of various machine learning (ML) algorithms in predicting progression, treatment response, and relapse and to assess their predictive power against that of the Cox proportional hazards (CPH) model in patients with early-stage MF.

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  • * Stem cell therapy, particularly using adipose tissue-derived mesenchymal stem cells (AD-MSCs), has been identified as a promising way to enhance healing in chronic wounds due to their availability and beneficial properties.
  • * Research shows that integrating stem cell treatments with local wound care can lead to improved healing outcomes, including reduced pain and faster recovery times, making it a strong candidate for treating chronic and difficult wounds.
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Ex vivo confocal microscope (EVCM) rapidly images freshly excised tissue at a histopathological resolution. EVCM features of keratinocyte skin cancers are well-established, but those of benign clinical mimickers remain scarce. We describe EVCM features of common benign lesions and compare them with their malignant differentials.

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Background: Reflectance confocal microscopy (RCM) has quickly transitioned from a research tool to an adjunct diagnostic bedside tool, providing the opportunity for noninvasive evaluation of skin lesions with histologic resolution. RCM is an optical imaging technique that uses near-infrared excitation wavelengths and safe low-power lasers. En-face images of different skin layers (up to the superficial dermis) are acquired in grayscale based on the reflective indices of tissue components.

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Cutaneous malignancies are common malignancies worldwide, with rising incidence. Most skin cancers, including melanoma, can be cured if diagnosed correctly at an early stage. Thus, millions of biopsies are performed annually, posing a major economic burden.

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Background: A broad spectrum of skin diseases, including hair and nails, can be directly or indirectly triggered by COVID-19. It is aimed to examine the type and frequency of hair and nail disorders after COVID-19 infection.

Methods: This is a multicenter study conducted on consecutive 2171 post-COVID-19 patients.

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  • The study investigates the relationship between total body nevus count (TBNC), nevus counts in specific locations, and risk factors for developing multiple primary cutaneous melanomas (MPCM) among melanoma patients.
  • A cohort of 156 patients (22 with MPCM and 134 with single primary melanoma) was analyzed, revealing that patients with MPCM had a significantly higher mean TBNC compared to those with single primary melanoma.
  • The significant findings suggest that having 10 or more nevi on the head and neck increases the likelihood of developing MPCM, highlighting the importance of monitoring nevus counts in melanoma patients.
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Introduction: The COVID-19 pandemic drastically changed the priorities in healthcare services; outpatient management of acne has changed during this period.

Objectives: We aimed to investigate treatment practices, outcomes and identify modified follow-up schedules applied during the pandemic.

Methods: The patients who were admitted to dermatology outpatient clinic between March 13 and July 13, 2020, were included.

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  • Childhood psoriasis affects about 128 out of every 100,000 children, and this study looked at the role of tobacco smoke exposure in its development among Turkish children.
  • The research included 130 children with psoriasis and 390 control children, using statistical methods to assess the risk factors associated with the condition.
  • Findings revealed that exposure to environmental tobacco smoke at home significantly increases the risk of developing childhood psoriasis, while intrauterine tobacco exposure showed no clear relationship.
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Background: Ten-year survival rates in mycosis fungoides (MF) broadly varies, however, there is no standardized prognostic index available. This is presumably due to low prevalence, heterogeneity, and diagnostic challenges in MF. Recent studies have focused on identifying objective prognostic indices by using different parameters for survival determinants.

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Congenital melanocytic naevi are hamartomas of the neuroectoderm caused by genetic mosaicism. Congenital melanocytic naevi are seen in 1-6% of all live births and commonly classified based on the projected size in adults. Congenital melanocytic naevi appear in different colours, shapes, and sizes, and occasionally present with complications.

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Synopsis of recent research by authors named "Mehmet Fatih Atak"

  • - Mehmet Fatih Atak's recent research encompasses various aspects of dermatology, including the efficacy of novel treatments for conditions like ulcerative dermatomyositis and the role of stem cells in wound healing, emphasizing the complex interplay of biological processes in skin repair.
  • - He has contributed to the understanding of non-invasive diagnostic techniques such as reflectance confocal microscopy and ex vivo confocal microscopy, enhancing the diagnostic accuracy for skin lesions and their benign and malignant distinctions.
  • - Atak's work also addresses the impact of social factors like the pharmaceutical industry's influence on academic dermatology, alongside investigating COVID-19's effects on hair and nail disorders, indicating a comprehensive approach to contemporary dermatological issues.