Bilateral papilledema caused by brucellosis mimicking pseudotumor cerebri.

In this article, we report a patient with migraine who was hospitalized with a prediagnosis of pseudotumor cerebri and diagnosed as neurobrucellosis with isolated intracranial hypertension presentation. A 22-year-old woman was admitted to emergency department with a complaint of headache. Her anamnesis indicated that she had migraine for 7 years.

Ptosis and Elevation Paresis Due to Mesencephalic Infarction.

Lesions located in the anterior cavernous sinus or posterior orbit are known to cause divisional oculomotor palsy. We herein report a patient with fascicular infarction causing superior division paresis of the nerve.

GNE Myopathy in Turkish Sisters with a Novel Homozygous Mutation.

Background. Hereditary inclusion body myopathy is caused by biallelic defects in the GNE gene located on chromosome 9p13. It generally affects adults older than 20 years of age.

Clinical and MRI findings of cerebellar agenesis in two living adult patients.

Cerebellar agenesis (CA) is an extremely rare entity. We present two adult patients with CA. The 61-year-old man had ataxia, dysarthria, abnormalities in cerebellar tests, severe cognitive impairment, and moderate mental retardation.

Valproate-associated reproductive hormone abnormalities: do bipolar men have the same risk as epileptic men?

Objective: The effects of valproate on male reproductive hormones have been studied in epileptic patients and animals, but the results are inconsistent because reproductive hormone abnormalities may be independent of the use of valproate and may be due to epilepsy itself. The aim of this study was to determine if there is an association between valproate and reproductive abnormalities in men with bipolar disorder or if the association is unique to men with epilepsy.

Materials And Method: The study included 39 male patients aged 18-50 years with a DSM-IV diagnosis of bipolar disorder (21 on lithium monotherapy and 18 on valproate monotherapy or valproate in combination with lithium therapy) and 15 male epilepsy patients on valproate monotherapy that were evaluated in terms of reproductive hormones.

Psychiatric comorbidity, quality of life and social support in epileptic patients.

Background: Epilepsy is accompanied by many psychiatric disorders and continues to be a disease that disturbs the functioning and quality of life (QOL) of patients.

Aims: To assess the frequency of psychiatric disorders occurring in epileptic patients, determine depression and anxiety levels, and compare the results with healthy controls. The effect of epilepsy on QOL and the effects of social support on epilepsy were also assessed.

Recovery of visual-field defects after occipital lobe infarction: a perimetric study.

Objective: To assess the temporal course of homonymous visual-field defects due to occipital lobe infarction, by using automated perimetry.

Methods: 32 patients with ischaemic infarction of the occipital lobe were studied prospectively, using a Humphrey Visual Field Analyser II. The visual field of each eye was divided into central, paracentral and peripheral zones.

Clinical and radiologic correlations of small and large centrum ovale infarcts.

Background: Acute centrum ovale (CO) infarction confined to the territory of perforating long medullary arteries is rarely reported. This study was designed to investigate the full spectrum of clinical findings, topography, and pathogenesis of patients with acute CO infarct.

Methods: A total of 64 patients with CO infarct were recorded.

Hemifacial spasm in correlation with electrophysiological and radiological findings.

Objective: To investigate the correlation between the electrophysiological and radiological findings of primary hemifacial spasm patients.

Subjects: Patients with primary hemifacial spasm who had had no botulinum toxin treatment previously were included in the study.

Design: In this prospective study patients underwent cerebral magnetic resonance imaging,a magnetic resonance angiography investigation and an electrophysiological examination after informed consent had be given by the patients.

Isolated hand palsy due to cortical infarction: localization of the motor hand area.

Objective: To evaluate the cortical presentation of the hand area according to MRI images of the infarcted area in patients who have predominantly hand weakness.

Background: "Pseudoperipheral palsy" is an old term employed to describe a rare clinical picture consisting of predominant weakness of the hand in association with cerebral infarction. Because the organization of the cortical efferent area of the hand has not been fully defined, this phenomenon merits attention.

Dysarthria due to supratentorial and infratentorial ischemic stroke: a diffusion-weighted imaging study.

Background And Purpose: Dysarthria characterized by slurring with imprecise articulation without evidence of aphasia is a frequent symptom in the acute phase of cerebral ischemia, although there is little knowledge on its anatomic specificity and spectrum of associated clinical characteristics regarding diffusion-weighted imaging (DWI).

Methods: An investigation of 101 consecutive patients with sudden-onset dysarthria due to a single or multiple lesions on DWI, corresponding to 8.7% of 1,160 patients with ischemic stroke, was made.

Interaction of botulinum toxin type A with local anesthetic agents: an experimental study with rabbits.

Injection of botulinum toxin is a painful procedure, limiting the number of patients treated. This study was designed to establish whether infiltration of local anesthetics plays a role in the effectiveness of botulinum toxin. For the study, 24 New Zealand white rabbits were divided into three groups.

Isolated dysarthria-facial paresis syndrome: a rare clinical entity which is usually overlooked.

Background And Aims: The aim of the study is to search the lesion localization of the pure isolated facial paresis-dysarthria syndrome in patients who were admitted to our neurology clinic in a prospective study.

Methods: Over a period of six years, the patients who had no prominent sensorimotor dysfunction were examined by neurologists and underwent computerized tomography (CT) and/or magnetic resonance imaging (MRI).

Results: Eleven patients out of more than 2000 had the aforementioned clinical picture.