Comparison of Effects of Opioid Analgesics on Spontaneous Proximal and Distal Colon Contractions in Healthy Rats and Rats with Peritonitis.

Objective: The goal of this study was to investigate and compare the effects of opioids on proximal and distal colon contractions in normal rats and rats with peritonitis, with and without the presence of naloxone in the environment.

Methods: The study was approved by Cumhuriyet University Ethics committee. In this study, 16 Wistar Albino male rats were used.