The Effect of Udenafil on Stasis Zone in an Experimental Burn Model.

Background: Management of the burn injuries is still a problematic issue because the stasis zone may become necrotic. We hypothesized that udenafil, a potent phospodiesterase inhibitor, can be beneficial in burn treatment by enhancing the viability of the stasis zone.

Methods: Fifteen Wistar rats were randomly divided into 3 groups.

Platelet-rich fibrin: An effective chronic wound healing accelerator.

Background: Platelets are cells that play a central role in wound healing, and they are the main source of the growth factor complex that plays the main role in natural wound healing. It is aimed to present the beneficial effects of topical application of PRF on chronic ulcers that do not respond to standard wound care in cases of chronic ulcers that require a long treatment process and high costs.

Materials And Methods: The study included 16 patients between the dates of January 2017 and September 2019.

Four Quadrant-Embedded Purse-String Closure for Defects of Benign Skin Tumors Post Circular Excision.

Objective: Skin wounds after elliptical removal of benign tumors, are conventially sutured linearly for closure and often result in longer and undesirable scars. We aimed to evaluate the efficiency of four quadrant embedded intradermal purse-string suture closure technique for round defects in order to obtain satisfactory cosmetic outcomes and limited scar.

Materials And Methods: We analysed the features of 143 patients for whom a total of 208 four quadrant embedded purse string sutures were used to completely close their postoperative surgical defects.

Effects of dabigatran and fondaparinux on degloving injuries: An experimental study.

Background: Management of the skin degloving injuries is still a problematic issue, and the avulsed part of the skin may become necrotic. We hypothesized that the anticoagulant pharmacological agents, fondaparinux and dabigatran may be beneficial in the treatment of degloving injuries by enhancing the viability of the reattached flap.

Methods: Twenty four Wistar rats were divided into three groups as follows: control group (Group 1), fondaparinux group (Group 2) and dabigatran group (Group 3).

Preoperative estimation of breast resection weight in patients undergoing inferior pedicle reduction mammoplasty: the Bilgen formula.

Background/aim: Symptomatic breast hypertrophy has a significant impact on the quality of life of women. The amount of tissue to be excised may be preoperatively estimated by an experienced surgeon. However, this remains a subjective assessment.

Disastrous Complications Following Rhinoplasty: Soft Tissue Defects.

Background: Rhinoplasty has become one of the most frequently performed worldwide aesthetic procedures thanks to the successful results obtained by plastic surgeons. In this study, soft tissue defects, encountered as an undesirable and fearsome complication following rhinoplasty, its causes and precautions are presented by authors.

Materials And Methods: Eight patients operated between December 2015 and December 2018 were enrolled in this study.

Our Treatment Approach in Pediatric Maxillofacial Traumas.

Background: Maxillofacial injuries in children are rarer in proportion in comparison to adult facial injuries, and they constitute 1% to 15% of all facial bone fractures. The causes and incidence of maxillofacial injuries in children differ based on social, cultural, and environmental factors.

Aim: The purpose of this study is to investigate the etiology, epidemiology, and type of injury in pediatric facial injuries, as well as analyzing types of fractures, related injuries, and treatment options.

The effect of oxidative stress and Raftlin levels on wound healing.

Reactive oxygen species (ROS) are crucial in all wound-healing processes. Raftlin also plays an important role in the induction of the autoimmune response and the vascular inflammatory response. Inflammatory mediators induce continuous synthesis and secretion.

Inferior and Central Mound Pedicle Breast Reduction in Gigantomastia: A Safe Alternative?

Gigantomastia has been described as excessive hypertrophy of the female breast, however, there is controversy about the weight of the excised tissue. In the literature, resected tissue amount between 1,000 g and 2,000 g per breast is reported as gigantomastia. : The aim of this study is to evaluate the results of the patients who underwent reduction mammaplasty with a resection amount of at least 1,000 g or above via inferior pyramidal pedicle breast reduction technique retrospectively.

Van der Woude Syndrome With a Novel Mutation in the IRF6 Gene.

Van der Woude syndrome (VWS) is a rare autosomal dominant disease, first reported in the literature in 1845 by Demarquay and subsequently thoroughly described in 1954 by Van der Woude. Van der Woude Syndrome is the most common form of syndromic orofacial clefting and individuals with this syndrome account for 2% of all cleft cases. Van der Woude syndrome clinically presents with congenital lip pits.

The Superficial Temporal Artery Island Flap: An Option for Moustache Reconstruction.

Vascular anomalies are a group of lesions originating from blood vessels and lymphatics with varying histology and clinical behavior. They form the most common congenital anomalies in infants and children. The reconstructive method for the facial region defects varies depending on the size and position of the defect, as well as the patient's age, health status and aesthetic concerns.

Isolated Congenital Cleft of the Nose.

The intrauterine growth of the face is formed by appropriate fusion of frontonasal, maxillary, and mandibular protrusions. These anomalies are very rare and there may be differences between individuals according to cleft types. In this article, a very rare condition of isolated alar cleft and its treatment method were presented.

The effect of increasing the contact surface on tendon healing.

Background: The most common complication after tendon repair is the development of adhesion, with subsequent rupture.

Methods: In this study, we present a new method in which the tendon healing contact surface is increased to reduce these complications. The tendons of chickens in groups 1, 3, and 5 were transversely cut and repaired with in the traditional fashion with double-modified Kessler method and 5/0 polypropylene.

Setleis syndrome: clinical, molecular and structural studies of the first TWIST2 missense mutation.

Setleis syndrome is characterized by bitemporal scar-like lesions and other characteristic facial features. It results from recessive mutations that truncate critical functional domains in the basic helix-loop-helix (bHLH) transcription factor, TWIST2, which regulates expression of genes for facial development. To date, only four nonsense or small deletion mutations have been reported.

[Closed reduction of zygoma tripod and isolated arch fractures with Volkmann bone hook].

Objectives: This study aims to investigate the effectiveness of closed reduction technique for the management of zygoma tripod or arch fractures without internal fixation.

Patients And Methods: Between June 2011 - December 2013, medical data of seven patients (2 females, 5 males; mean age 49.1 years; range 34 to 76 years) who were treated using closed reduction technique with Volkman bone hook due to zygoma tripod and isolated arch fractures were retrospectively analyzed.

An frontalis sling operation using an autogenous en-bloc, fan-shaped tensor fascia lata graft for blepharoptosis.

This article presents a modification of the frontalis sling operation for severe blepharoptosis with poor levator function. The fascia or other suspension materials are usually used in strip form to avoid a mass under the skin and lid-crease obliteration in the frontal sling operations. However, the 'strip-sling technique' carries the risk of some complications including irregular eyelid contour, unstable fixation and loss of elevating power in the follow-up period.

Reconstruction of large anterior scalp defects using advancement flaps.

Reconstruction of the scalp may be challenging for reconstructive surgeons because of the special anatomic structure of the scalp and underlying skeleton. Anterior scalp defects especially deserve special care for pleasant hairline re-creation and redirection of hair follicles. Local transposition or rotation flaps are the most common reconstruction methods for moderate or large anterior scalp defects.

Use of rotation flap in repair of cleft palate and velopharyngeal insufficiency.

Although cleft palate anomaly is frequent, the criterion standards in surgical treatment have not been determined yet. There are a few techniques described for cleft palate repair owing to the limited tissue in the palatal mucosa, the rigid structure of the palatal mucosa, and the limited vascularity of the hard palate. In this study, a novel cleft palate repair technique based on separating the soft palate from the hard palate as a musculomucosal flap and using it as a rotation flap has been described.

Immunohistochemical prognostic criteria in xeroderma pigmentosum.

Xeroderma pigmentosum (XP) is a rare inheritable disease characterized by severe sun sensitivity and early development of skin cancers. We compared the expression of cell proliferation markers and cell cycle checkpoint regulators in squamous cell carcinomas (SCC) and basal cell carcinomas (BCC) from patients with and without XP. Immunostaining for p53, Ki-67, and proliferating cell nuclear antigen (PCNA) was determined in SCCs and BCCs from 18 XP patients and 30 controls.

Comparison of classification systems for congenital melanocytic nevi.

Background: Congenital melanocytic nevi (CMNs) are found in approximately 1% of newborn infants, but these represent only a small proportion of the total population of nevi. They vary widely in size, from a small spot to a large area. Later in childhood, these lesions become thickened, verrucous, and hairy.

The effects of exogenous melatonin on peripheral nerve regeneration and collagen formation in rats.

Background: Peripheral nerve damage that requires surgical repair does not result in complete recovery because of collagen scar formation, ischemia, free oxygen radical damage, and other factors. To date, the best treatment method has not yet been determined. In this study, we designed an experimental peripheral nerve injury model, and researched the possible effects of melatonin hormone, based on evidence of its strong antioxidant and cell-protective effects via mimicking the effects of calcium channel blockers.

Congenital lateral cleft palate and lateral palatal synechiae.

We report a sporadic case of congenital lateral cleft palate and lateral palatal synechiae and suggest that its mechanism is embryonal. This is the first published case that we know of with cleft palate-lateral synechiae syndrome including the lateral cleft palate.

Polydactyly and hypertension.

A case diagnosed as Bardet-Biedl syndrome with polydactyly and hypertension has been presented here. Bardet-Biedl syndrome is an autosomal recessive disorder, which includes renal dystrophy, dystrophic extremities (often polydactyly), obesity, hypogenitalism, renal disease, and mental retardation. It was first described by John Z.