Types and Rates of COVID-19 Vaccination in Patients With Newly Diagnosed Microsatellite Stable and Instable Non-Metastatic Colon Cancer.

Introduction Microsatellite instable (deficient mismatch repair, dMMR) colon cancer is associated with hypermutability and immune infiltration-activation. COVID-19 vaccines stimulate immune-inflammation response. This study aimed to investigate the types and rates of COVID-19 vaccines in patients with newly diagnosed colon cancer and compare it according to the microsatellite status.

Lateral Lymph Node Dissection for Locally Advanced Rectal Carcinoma: A Step-by-Step Description of Surgical Anatomical Planes During Cadaveric Dissection and Minimally Invasive Surgery.

Purpose: Total mesorectal excision (TME) is accepted as gold standard method in rectal cancer globally. But there is no standard for lateral lymph nodes. Combination of neoadjuvant treatment plus lateral lymph node dissection (LLND) in select patients might be a promising method.

Short-Course Radiotherapy Followed by Consolidation Chemotherapy Is Safe and Effective in Locally Advanced Rectal Cancer: Comparative Short-term Results of Multicenter Propensity Score Case-Matched Study.

Background: Consolidation chemotherapy strategies have demonstrated improved pathological complete response and tumor downstaging rates for patients diagnosed with rectal cancer.

Objective: This study aimed to compare perioperative outcomes and pathological complete response rates among different neoadjuvant treatment strategies in patients undergoing total mesorectal excision for locally advanced rectal cancer.

Design: Propensity score case-matched study.

Does Pre-procedural Anxiety Affect the Consumption of Sedatives During Colonoscopy?

Objective: Anxiety is an unpleasant emotional stat with systemic effects. The anxiety level of the patients may increase the requirements for sedation during colonoscopy. The aim of the study was to evaluate the effect of pre-procedural anxiety on the dose of propofol.

Standardization of the Definition and Surgical Management of Splenic Flexure Carcinoma by an International Expert Consensus Using the Delphi Technique: Room for Improvement?

Background: Surgical management of splenic flexure carcinoma remains controversial.

Objective: This study aimed to establish an expert international consensus on splenic flexure carcinoma management.

Design: A 3-round online-based Delphi study was conducted between September 2020 and April 2021.

Comparison of textbook versus three-dimensional animation versus cadaveric training videos in teaching laparoscopic rectal surgery: a prospective randomized trial.

Aim: The aim of this prospective randomized study was to compare the effectiveness of various educational tools in laparoscopic rectal surgery, including surgical textbooks, animation and cadaveric videos.

Method: Initially, an electronic assessment test assessing knowledge of laparoscopic rectal surgery was created and validated. The test was sent to graduates completing a general surgery residency programme in Turkey, who were then randomized into four groups based on the type of study material.

Effect of Prehabilitation on Stoma Self-Care, Anxiety, Depression, and Quality of Life in Patients With Stomas: A Randomized Controlled Trial.

Background: An intestinal stoma has severe psychosocial effects on patients.

Objective: This study aimed to measure the effects of prehabilitation on stoma self-care, quality of life, anxiety, and depression levels.

Design: This study was a a randomized controlled trial.

Psychiatric Symptoms, Aggression, and Sexual Dysfunction Among Patients With Benign Anal Conditions.

Introduction: The aim of this study was to investigate the incidence of general psychiatric symptoms, aggression levels, and sexual dysfunction in patients with benign anorectal diseases and compare the results with those of healthy control subjects.

Methods: We prospectively enrolled consecutive adult patients who presented for treatment of benign perianal diseases and healthy control subjects between June 2017 and December 2018. All patients had either grade 3 or 4 hemorrhoidal disease or perianal fistula with active discharge who had not undergone previous anorectal surgery.

Platelet-rich plasma treatment improves postoperative recovery in patients with pilonidal sinus disease: a randomized controlled clinical trial.

Background: Pilonidal sinus is a common health problem. The current study aimed to compare the impact of autologous platelet-rich plasma (PRP) with that of minimally invasive techniques in terms of pain reduction, return to daily activities, quality of life, and duration of wound healing after open excision and secondary closure.

Methods: Patients who were over 18 years old and had chronic PS disease between March 2018 and January 2019 were enrolled and randomly divided into three groups.

Quality of life after colorectal surgery: A prospective study of patients compared with their spouses.

Background: Although radical surgery for colorectal cancer improves the oncological outcomes, a significant portion of patients suffer from alterations in their quality of life (QoL). There are many studies investigating the QoL of patients who have colorectal cancer but none of these focus on the QoL of spouses.

Aim: To compare the QoL of patients after colorectal surgery to the QoL of spouses.

Development and Implementation of a Novel Computer-Based Training Module for the Standardization of Splenic Flexure Mobilization.

Background: Computer-based training modules use various multimedia components such as text, graphics, animation, and videos that can theoretically facilitate the learning process. Splenic flexure mobilization (SFM) is a crucial step for tension-free colorectal/anal anastomosis that can be a technically demanding step. This study is designed to demonstrate our novel training module for SFM with high-vessel ligation during surgery and present the anatomical landmarks and embryological plans for SFM.

Redefining the collateral system between the superior mesenteric artery and inferior mesenteric artery: a novel classification.

Aim: The aim of this study was to evaluate the arterial collateral vasculature between the superior mesenteric artery and the inferior mesenteric artery (IMA) from a surgical perspective.

Method: A total of 107 fresh adult cadavers (94 male) were studied with emphasis on the vascular anatomy of the left colon. Dissections were carried out mimicking the anterior resection technique.

Abdominal palpation and percussion maneuvers do not affect bowel sounds.

Objectives: Medical textbooks suggest that the frequency of bowel sounds may be altered by performing auscultation after palpation or percussion. We hypothesize that the frequency of bowel sounds is not affected by the order of abdominal examination.

Material And Methods: Both healthy volunteers (n= 80) and patients (n= 100) were enrolled in this crossover randomized study.

Fall of another myth for colon cancer: Duration of symptoms does not differ between right- or left-sided colon cancers.

Background/aims: Patients with colorectal cancer continue to present with relatively advanced tumors that are associated with poor oncological outcomes. The aim of the present study was to assess the association between localization, symptom duration, and tumor stage.

Materials And Methods: A prospective, multicenter cohort study was conducted on patients newly diagnosed with a histologically proven colorectal adenocarcinoma.

Effects of abdominal and vaginal hysterectomy on anorectal functions along with quality of life of the patient.

Objectives And Background: Hysterectomy is the most commonly performed major gynecological operation for both benign and malign gynecologic conditions. After hysterectomy, although some investigators have declared an increased incidence of urinary and anorectal dysfunction, some others could not show any connection.

Methods: The voluntary patients were divided in two groups: abdominal hysterectomy (Group 1) and vaginal hysterectomy (Group 2).

Comparison of Mesenteric Lengthening Techniques in IPAA: An Anatomic and Angiographic Study on Fresh Cadavers.

Background: The IPAA technique restores anal functionality in patients who have had the large intestine and rectum removed; however, 1 of the most important reasons for pouch failure is tension on the anastomosis.

Objective: The aim of this study was to compare technical procedures for mesenteric lengthening used for IPAA to reduce this tension.

Design: After randomization, 4 different techniques for mesenteric lengthening were performed and compared on fresh cadavers.

Effects of Hysterectomy on Pelvic Floor Disorders: A Longitudinal Study.

Background: Hysterectomy might adversely affect pelvic floor functions and result in many different symptoms, such as urinary and anal incontinence, obstructed defecation, and constipation.

Objective: The aim of this prospective study was to evaluate the influence of hysterectomy on pelvic floor disorders.

Design: This was a prospective and longitudinal study.

Variations in the Vascular Anatomy of the Right Colon and Implications for Right-Sided Colon Surgery.

Background: Knowledge of the normal pattern and variations of the blood supply of the right colon is crucial for better outcomes after colon surgery.

Objective: The purpose of this study was to describe the precise vascular anatomy of the right colon according to surgical perspective.

Design: Adult fresh cadavers were dissected between January 2013 and October 2015, focusing on the venous and arterial anatomy of the right side of the colon.

Phenol Injection Versus Excision With Open Healing in Pilonidal Disease: A Prospective Randomized Trial.

Background: Minimally invasive procedures may be an alternative to surgical excisions for pilonidal disease.

Objective: The aim of the study was to compare phenol injection versus excision with open healing technique.

Design: This is a prospective randomized study (ACTRN12612000868886).

Dynamic article: surgical anatomical planes for complete mesocolic excision and applied vascular anatomy of the right colon.

Background: Lower local recurrence rates and better overall survival are associated with complete mesocolic excision with central vascular ligation for treatment of colon cancer. To accomplish this, surgeons need to pay special attention to the surgical anatomical planes and vascular anatomy of the colon. However, surgical education in this area has been neglected.

The role of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the primary staging of rectal cancer.

Background: In this study we aimed to determine the need for 18F-flourodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in the preoperative staging of rectal carcinoma in our large patient group according to level and location of tumor.

Method: Totally, 97 patients diagnosed with primary rectal adenocarcinoma between May 2009 and July 2011 were included in the study. Preoperative staging was performed by evaluating contrast-enhanced thoracic, abdominal, and pelvic computed tomographies.

Important points for protection of the autonomic nerves during total mesorectal excision.

Background: One of the most important aspects for patients undergoing rectal cancer surgery is quality of life, which is closely related to postoperative sexual, urinary, and bowel functions. To preserve these functions, surgeons need to pay special attention to the fascial planes and autonomic nerve plexuses.

Objective: The aim of this study is to describe the locations of autonomic nerves in critical areas and to demonstrate the correct surgical planes for protecting these nerves during total mesorectal excision.