Publications by authors named "Mehmet Akif Eryılmaz"

Purpose: Psoriasis is an autoimmune pathology characterized by chronic inflammation with known multiorgan involvement. In the literature, there are few studies investigating the effects of psoriasis on upper respiratory tract mucosa. Our aim in our study was to investigate the possible effect of psoriasis disease severity and duration on nasal mucosa.

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Background: This study aimed to investigate thymoquinone (TQ), and melatonin's radioprotective effects on liver, parotid gland, brain, and testis of rats which were exposed to total body irradiation (IR).

Methods: Thirty adult Wistar rats were randomly divided into four groups that are Group 1 (control group): total body IR only, Group 2: IR-Melatonin (10 mg/kg), Group 3: IR-TQ (10 mg/kg), and Group 4 (sham group): nothing. Total body IR dose was 6 Gy.

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Background: Dorsal preservation surgeries in which the subperichondral and subperiosteal planes are used to elevate the soft tissue envelope of the nose have become increasingly widespread because they can reduce postoperative edema and promote faster healing. However, the effects of surgical dissection planes on the viability of cartilage grafts are not known.

Objective: The aim of this study was to determine, in a rabbit model, the viability of diced cartilage grafts in different rhinoplasty dissection planes (sub-superficial musculoaponeurotic system [SMAS], subperichondral, subperiosteal).

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Background: Subdorsal septal resection and radix osteotomy are distinctive surgical steps in preservation rhinoplasty.

Objectives: The aim of this study was to evaluate the nasal bone thickness, the level of the septal bony-cartilaginous junction (K area), and the distances of the frontal sinus and skull base from the transverse osteotomy line in the Turkish population by means of conventional computed tomography (CT).

Methods: A retrospective evaluation was made of 203 consecutive preoperative paranasal CT scans of patients (classified in terms of age and gender) who had undergone rhinoplasty surgery between January 2020 and June 2021.

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Teratomas are benign tumours containing tissues derived from ectoderm, endoderm and mesoderm Epignathus is a rare congenital teratoma and originates from oropharyngeal region. We present a case of giant epignathus arising from tonsillar region in a neonate. A male neonate that was born with a 38-week cesarean section presented with a pedunculated mass from left tonsilla palatina and protruding outside the mouth.

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Background: We aimed to evaluate whether C-reactive protein(CRP)/ Albumin ratio (CAR) performed in the early postoperative period after total laryngectomy could be a predictive factor for the development of pharyngocutaneous fistula (PCF).

Methods: The files of patients with laryngeal squamous cell carcinoma who underwent total laryngectomy between January 2005 and January 2019 were retrospectively reviewed. Patients were divided into two groups: patients with PCF (PCF group) and without (Non-PCF group).

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Objective: This study aimed to determine whether administration of topical and intraperitoneal zinc for maxillofacial fractures has any impact on the bone healing process.

Material And Method: Thirty-two New Zealand rabbits were randomly assigned to four groups of eight each. The first group was the control group; fracture lines were fixed using titanium microplates and no medication was administered.

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Current data do not support the routine use of any agent to prevent cisplatin ototoxicity. Although there are various diseases in which derivatives of vitamin A are used due to their antioxidant effects, there is no study for prevention from ototoxicity. In this study, the protective effect of isotretinoin was investigated on cisplatin ototoxicity in rats.

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Introduction: It is known that hyperlipidemia reduces hearing functions. In this study, we aimed to study the effect of antihyperlipidemic drugs on hearing functions and tinnitus.

Methods: Eighty-four patients aged 18 to 84, who were diagnosed with hyperlipidemia and started treatment with the statin group (atorvastatin 20 mg and 40 mg, rosuvastatin 10 mg and 20 mg, and simvastatin 20 mg) of antihyperlipidemic drugs, were included in this study.

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Purpose: To evaluate the prognostic value of maximal standardized uptake values (SUV) from serial fluor-18-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) in patients with nasopharyngeal carcinoma (NPC).

Materials And Methods: Fifty-two patients with NPC who underwent F-FDG PET/CT scan before radiotherapy with/without chemotherapy were reviewed retrospectively. Twenty-seven patients (52%) were applied 3-D conformal radiotherapy and 25 patients (48%) applied intensity-modulated radiotherapy (IMRT).

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Purpose: We aimed to investigate the protective effect of melatonin in radiotherapy-induced thyroid gland injury in an experimental rat model.

Materials And Methods: Thirty-two rats were divided into four groups: the control group, melatonin treatment group, radiotherapy group and melatonin plus radiotherapy group. The neck region of each rat was defined by simulation and radiated with 2 Gray (Gy) per min with 6-MV photon beams, for a total dose of 18 Gy.

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Article Synopsis
  • Benign paroxysmal positional vertigo (BPPV) is a common type of vertigo that patients often report when visiting neurology and ENT clinics.
  • Diagnosis and treatment involve specific maneuvers to identify the affected canal by observing nystagmus signs, but complications can arise with multiple canal involvement.
  • The case discussed involves a patient with BPPV caused by trauma and multiple canal issues, which posed challenges and made the condition resistant to typical treatments.
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Sudden bilateral hearing loss are seen rarely and the toxic substance exposure constitutes a small part of etiology. A Fifty-eight-year-old woman admitted to our clinic with sudden bilateral hearing loss shortly after chlorpyrifos-ethyl exposure. Otolaryngologic examination findings were normal.

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Background/aims: Since the initial use in 1981 by Wigand, different endoscopic endonasal surgery techniques have been proposed to close ventral skull base defects, all of which include multilayer closure involving vascularized mucoseptal flaps, autologous grafts, and synthetic materials. These methods are used individually or in combination, as required by the operative condition.

Methods: In this study we aimed to describe our endoscopic technique using inlay-outlay fascia lata and autologous fat with fibrin sealant to close spontaneous and traumatic cerebrospinal fluid (CSF) rhinorrhea.

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Objectives: Cholesteatoma is a chronic inflammatory clinical disorder, and it may cause hearing loss and various complications due to its destructive nature. Mean platelet volume (MPV) is a prothrombotic and proinflammatory marker. The aim of this study is to investigate predictive values of MPV, neutrophil-to-lymphocyte ratio, erythrocyte distribution width, and platelet lymphocyte ratio in cholesteatomatous or noncholesteatomatous pediatric chronic otitis media.

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Lipomas are benign mesenchymal tumors that can be observed all over the body. In total, 25% of lipomas are observed in the head and neck region, and most of them are located in the posterior cervical triangle. Lipomas that are greater than 10 cm in width or more than 1000 g in weight are called giant tumors.

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Familial Mediterranean Fever (FMF) is a progressive disease characterized by chronic inflammation, which also has negative effects on cochlear functions and hearing levels. We investigated whether the cochlear functions and hearing levels of FMF patients were different than healthy controls and also evaluated the relationship of hearing levels with the age at diagnosis, duration without treatment, and inflammation and lipid parameters in this study. A total of 60 patients diagnosed with FMF and 48 age, gender and body mass index (BMI)-matched healthy controls were included in the study.

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Article Synopsis
  • The study assesses the prevalence of serous otitis media (SOM) in school-age children from rural Konya, Turkey, involving 2,352 children over four months.
  • Findings show an overall SOM prevalence of 4.6%, peaking at 11.2% in four-year-olds and 11.1% in six-year-olds, with higher rates in males (6.17%) compared to females (3.16%).
  • The study concludes that SOM prevalence is lower than reported in other literature and suggests the need for better preventive and therapeutic strategies in primary health care.
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Article Synopsis
  • * It involved 62 adult patients who were randomly assigned to either frequent debridement occurring at weeks 1, 2, and 4, or a single debridement at week 1.
  • * Results showed that the single debridement group experienced less discomfort and negative effects on work compared to the frequent debridement group, with no significant differences in overall quality of life and endoscopic scores between the two groups after 24 weeks.
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Malignant peripheral nerve sheath tumors are uncommon neoplasms that arise out of Schwann cells from the peripheral nerves, which rarely occur in the paranasal sinuses and nasal cavity. Especially with the increasing long-term survival of patients with nasopharynx carcinoma, second primary cancers can be diagnosed. Second primary cancers are not uncommon in patients with the prior radiation therapy.

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Anterior cervical osteophytes are excessive bony formation of cervical vertebra bodies. They are common but rarely symptomatic lesions mostly seen in geriatric population. Large anterior cervical osteophytes may cause symptoms such as dysphagia, dyspnea, dysphonia, and odynophagia.

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Hemangiomas are frequent benign hereditary vascular tumors. Intramuscular hemangiomas, a distinctive type of hemangioma occurring within the skeletal muscle, account for less than 1% of all hemangiomas. They occur more often in the trunk and extremity muscles, whereas the involvement of the temporal muscle is extremely rare.

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Objective: To determine the frequency of congenital hearing loss (CHL) in healthy newborn infants in Konya, Turkey.

Methods: A total of 43,503 healthy neonates born at Doctor Faruk Sükan Obstetrics and Children's Hospital between the years of 2006 and 2011 were evaluated, prospectively. Hearing screening test was carried out using Transient Evoked Otoacoustic Emission (TEOAE) method.

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Aim: To evaluate the results, complications, effectiveness, and operative results of the endocanalicular laser dacryocystorhinostomy (ECL DCR) in the distal obstructions of the lacrimal drainage system.

Methods: Sixty eyes of 57 patients who had a diagnosis of distal obstruction of the lacrimal drainage system were evaluated retrospectively in this study. All patients underwent ECL DCR by diode laser between October 2008 and July 2009.

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Synopsis of recent research by authors named "Mehmet Akif Eryılmaz"

  • - Mehmet Akif Eryilmaz's recent research focuses on the effects of various medical conditions and treatments on the respiratory and auditory systems, highlighting the interplay between autoimmune diseases, such as psoriasis, and nasal mucociliary clearance.
  • - His studies also investigate radioprotective agents like melatonin and thymoquinone in preserving organ function after radiation exposure, as well as the impact of surgical techniques on graft viability in rhinoplasty procedures.
  • - Additionally, Eryilmaz examines the predictive value of biomarkers like the C-reactive protein/albumin ratio for postoperative complications in laryngectomy patients, emphasizing the importance of preoperative assessments in surgical outcomes.