Publications by authors named "Mehmet A Dundar"

Background/aim: Early detection and prognosis of sepsis in critically ill children is crucial. The aim of this research was to investigate the prognostic ability of pancreatic stone protein (PSP) in validating sepsis and predicting mortality in a prospective observational study.

Materials And Methods: In a single-center study, pediatric intensive care unit patients were divided into cohorts of confirmed and suspected sepsis, as well as survivors and nonsurvivors.

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Objective: The objective of this study was to assess the effectiveness and safety of levosimendan as an alternative treatment for pediatric patients with decompensated heart failure unresponsive to conventional inotropes and to emphasize its role in enhancing cardiovascular stability.

Methods: A total of 15 pediatric patients with decompensated heart failure, stemming from acute fulminant myocarditis (53.3%) and post-congenital heart disease surgery complications (46.

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Objective: To reveal the reliability of radiological measurements of the ethmoid arteries.

Method: Five fresh frozen cadaveric heads underwent computed tomography and endoscopic sinus surgery. The lateromedial length of the anterior ethmoidal artery (AEA) and its distance to the axilla of the middle turbinate (MTA), the sphenoethmoidal recess (SR) and the posterior ethmoidal artery were measured.

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Background: Dorsal preservation surgeries in which the subperichondral and subperiosteal planes are used to elevate the soft tissue envelope of the nose have become increasingly widespread because they can reduce postoperative edema and promote faster healing. However, the effects of surgical dissection planes on the viability of cartilage grafts are not known.

Objective: The aim of this study was to determine, in a rabbit model, the viability of diced cartilage grafts in different rhinoplasty dissection planes (sub-superficial musculoaponeurotic system [SMAS], subperichondral, subperiosteal).

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Objective: To describe the anatomy of the lacrimal sac in relation to the lateral nasal wall by cadaver dissection, and to measure the distances of surgically important landmarks from relevant structures for safer and more efficient surgery.

Method: A total of 12 endoscopic dacryocystorhinostomy (DCR) were performed on both sides (right and left) of 6 fresh-frozen cadavers. The distances of the lacrimal sac to the posterior edge of the uncinate process, the frontal process of the maxilla, the maxillary ostium, the nasal vestibule, the middle turbinate attachment and the inferior turbinate were measured.

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Background/objective: There exists limited information in the literature on dominant hand preference in relation with vHIT applications. The present study aimed to examine the relationship between the clinician's dominant use of right- or left-hand and vHIT results.

Methods: A Synapsys vHIT Ulmer device was used in the study.

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Silver nanoparticles (AgNPs) have been recognized for their outstanding antibacterial activities, which are required for antibacterial coating materials in therapeutic applications. A bacterial-resistant electrospun nanofibrous mat made of polycaprolactone (PCL) in combination with polylactide acid (PLA) containing silver nanoparticles encapsulated with (thyme) extract (eAgNPs) was fabricated in order to assess the potential of applicability in biomedical applications such as cancer treatment, wound healing, or surgical sutures. In the current study, PCL and PLA used as the basis polymers were blended with biosynthesized eAgNPs, pure AgNPs, and thyme extract (TE) to observe the effects of additives in terms of antibacterial and anticancer activity and morphologic, thermal, mechanical, biocompatibility, and biodegradability properties.

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Background: The short- and long-term effects of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on the medial olivocochlear reflex and outer hair cells in the cochlea remain largely unclear.

Aims: The aim of this study was to investigate the efferent auditory system effects in adult patients with COVID-19.

Materials And Methods: The study included 18-50 years old 44 volunteers: 26 individuals (52 ears) with COVID-19 in the study group and 18 healthy individuals (36 ears) in the control group.

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Background: Subdorsal septal resection and radix osteotomy are distinctive surgical steps in preservation rhinoplasty.

Objectives: The aim of this study was to evaluate the nasal bone thickness, the level of the septal bony-cartilaginous junction (K area), and the distances of the frontal sinus and skull base from the transverse osteotomy line in the Turkish population by means of conventional computed tomography (CT).

Methods: A retrospective evaluation was made of 203 consecutive preoperative paranasal CT scans of patients (classified in terms of age and gender) who had undergone rhinoplasty surgery between January 2020 and June 2021.

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Introduction: Vitamin B 12 (cobalamin) deficiency may be a significant cause of hyperhomocysteinemia, and high homocysteine (Hcy) levels are associated with an increased risk of cardiovascular disease. Endothelium-derived microparticles (EMPs) are a new marker in endothelial dysfunction and atherosclerosis, which play a role in cardiovascular diseases' pathogenesis. This study aimed to evaluate the EMPs, the markers of endothelial dysfunction and atherosclerosis, and lipid profile in teenagers with cobalamin deficiency.

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Objective: This study aimed to assess the relationship between antioxidant enzymes such as glutathione peroxidase (GSH-Px), glutathione reductase (GSH-R), and paraoxonase (PON1) and carotid intima-media thickness (CIMT) and investigate susceptibility to atherosclerosis with decreasing antioxidant capacity in adolescent patients with iron deficiency (ID) and irondeficiency anemia (IDA).

Material And Methods: Twenty-five patients with IDA (14.9±1.

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Objective: Vitamin B12 deficiency induces hyper-hyperhomocysteinemia by inhibiting intracellular methionine re-methylation. Hyper-hyperhomocysteinemia increases the risk of atherosclerosis. Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase and its level elevates in cardiovascular diseases.

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Article Synopsis
  • This study aimed to explore how endoscopes can effectively visualize neural and vascular structures in the cerebellopontine angle (CPA) region through a minimally invasive approach using a specified anatomical point in the retrosigmoid area.
  • The research involved a surgical simulation on 10 fresh cadaver heads, where a small craniotomy was created to test an innovative endoscope cannula alongside different angled endoscopes for capturing detailed views of the CPA.
  • Results showed that with the endoscope cannula, surgeons could effectively use both hands during the procedure, enhancing their maneuverability and potentially leading to better outcomes in minimally invasive endoscopic surgery.
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Introduction: This study presents the current prevalence of anxiety, mood, and personality disorders as well as factors associated with the existence of psychiatric disorders in patients with benign paroxysmal positional vertigo (BPPV).

Methods: The study sample comprised 46 patients with BPPV and 74 control subjects. Anxiety and mood disorders were ascertained via the Structured Clinical Interview for the Diagnostic and Statistical Manual (DSM) of Mental Disorders, Fourth Edition/Clinical Version.

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Purpose: We aimed to investigate the protective effect of melatonin in radiotherapy-induced thyroid gland injury in an experimental rat model.

Materials And Methods: Thirty-two rats were divided into four groups: the control group, melatonin treatment group, radiotherapy group and melatonin plus radiotherapy group. The neck region of each rat was defined by simulation and radiated with 2 Gray (Gy) per min with 6-MV photon beams, for a total dose of 18 Gy.

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This study aimes to evaluate platelet and leucocyte indicators, such as the mean platelet volume, platelet distribution width, plateletcrit, white blood cell count, neutrophil to lymphocyte ratio in nasopharyngeal cancer patients and also to evaluate the relationship between these indicators and nasopharyngeal cancer with distant metastasis. The medical records of 118 patients diagnosed with nasopharyngeal cancer in our hospital between January 2006 and August 2015 were reviewed. The nasopharyngeal cancer group was further sub grouped according to the presence or absence of distant metastasis and TNM (tumour - T, node - N, metastasis - M) classification.

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Introduction: To manage the complications of irradiation of head and neck tissue is a challenging issue for the otolaryngologist. Definitive treatment of these complications is still controversial. Recently, hyperbaric oxygen therapy is promising option for these complications.

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Article Synopsis
  • Benign paroxysmal positional vertigo (BPPV) is a common type of vertigo that patients often report when visiting neurology and ENT clinics.
  • Diagnosis and treatment involve specific maneuvers to identify the affected canal by observing nystagmus signs, but complications can arise with multiple canal involvement.
  • The case discussed involves a patient with BPPV caused by trauma and multiple canal issues, which posed challenges and made the condition resistant to typical treatments.
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Sudden bilateral hearing loss are seen rarely and the toxic substance exposure constitutes a small part of etiology. A Fifty-eight-year-old woman admitted to our clinic with sudden bilateral hearing loss shortly after chlorpyrifos-ethyl exposure. Otolaryngologic examination findings were normal.

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Using a micromanipulation technique, a planar photonic crystal nanocavity made from a thin semiconductor membrane is released from the host semiconductor and attached to the end facet of a standard single-mode optical fiber. The cavity spectrum can be read out through the fiber by detecting the photoluminescence of embedded quantum dots. The modified fiber end serves as a fiber-optic refractive index sensor.

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