Publications by authors named "Mehlig K"

Over recent decades, there has been a simultaneous increase in income inequality and adverse mental health outcomes among adolescents in Western countries and especially in Sweden. Prior research on the relationship between income inequality and mental health has primarily focused on studies involving adults, yielding diverse findings regarding the nature of their association. Given the importance of relationships and comparisons to peers in immediate vicinity, we aimed to investigate the impact of neighborhood income inequality on mental health problems among seven-graders in Western Sweden.

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Background: Childhood maltreatment has detrimental health consequences. Risk for economic marginalization in adulthood is less clear.

Objective: To assess prospective associations between sexual abuse, paternal rejection and maternal rejection in childhood and indicators of economic marginalization.

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Objectives: To investigate the associations between stress resilience in late adolescence and later risk of severe COVID-19 and other lower respiratory infections. A secondary aim was to examine potential confounding between low cardiorespiratory fitness (CRF) and stress resilience in relation to respiratory infection.

Methods: We conducted a registry-based cohort study of 1.

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Article Synopsis
  • The study aimed to explore the relationship between mental and work-related stress and sick leave incidence over one year among middle-aged working women in Gothenburg, Sweden.
  • The research included 573 women, with 493 providing complete data, and found that 16% experienced sick leave, with chronic stress significantly increasing this risk.
  • Key findings highlighted that conflicts at work and low decision-making authority were strongly linked to increased sick leave, suggesting these factors are crucial for workplace interventions aimed at improving women's health.*
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Article Synopsis
  • - The study analyzed the relationship between alcohol consumption and metabolic syndrome (MetS) using data from 3,051 adults in the Swedish INTERGENE cohort, identifying different definitions of MetS (ATP III, IDF, JIS) and their varying prevalence rates.
  • - Results indicated that medium to high alcohol consumption was linked to lower odds of MetS, while abstainers showed no significant differences; prevalence estimates for MetS ranged from 13.9% to 25.3%, with men generally being more affected than women.
  • - The findings suggest that the impact of alcohol on MetS varies depending on the definition used, specifically that those meeting the strictest MetS criteria (ATP III) might actually benefit from
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Purpose: To determine the cross-sectional association between eating behavior in terms of the three-factor eating questionnaire (TFEQ) and adiposity measures.

Methods: The TFEQ-R21 was administered to 573 women aged 38 and 50 who participated in the population study of women in Gothenburg 2016/17. Three domains, emotional eating (EE), uncontrolled eating (UE), and cognitive restraint (CR) were examined as outcomes as well as predictors of adiposity outcomes.

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Background: Lyme borreliosis (LB) of the heart is called Lyme carditis (LC), which often manifests with high-grade atrioventricular block (AVB) requiring pacemaker implantation. LC is treated with antibiotics, and most patients recover fully after treatment. The overall incidence of LC, and of LC as a cause of pacemaker implantation, has not previously been systematically studied.

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Objective: This study examined BMI in young men and incident site-specific cancer to estimate population attributable fractions due to BMI based on projected obesity prevalence.

Methods: A population-based cohort study with measured height and weight at age 18. Cox regression models assessed linear associations for BMI and included age, year, and site of conscription as well as parental level of education as covariates.

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Background: Our aim was to assess associations between cardiorespiratory fitness (CRF) and body mass index (BMI) in youth and 5-year mortality after site-specific cancer diagnoses in men.

Methods: Men with cancer from a population who underwent military conscription at ages 16-25 during 1968-2005 in Sweden were included. CRF was assessed as maximal aerobic workload on a cycle ergometer test and was classified as low, moderate, or high.

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Background And Aims: Evidence shows that migrant children have a higher risk of developing obesity than those with native parents. We aimed to investigate the association between parental migration background and cardiometabolic health in children and adolescents in Europe.

Methods And Results: We included 8745 children aged 2-17 from the second follow-up of the European IDEFICS/I.

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Objectives: To assess the associations between cardiorespiratory fitness (CRF) in young men and the incidence of site-specific cancer.

Methods: A Swedish population-based cohort study with register linkage of men who underwent military conscription in 1968-2005 was undertaken. CRF was assessed by maximal aerobic workload cycle test at conscription.

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Aims/hypothesis: There is increasing evidence for the existence of shared genetic predictors of metabolic traits and neurodegenerative disease. We previously observed a U-shaped association between fasting insulin in middle-aged women and dementia up to 34 years later. In the present study, we performed genome-wide association (GWA) analyses for fasting serum insulin in European children with a focus on variants associated with the tails of the insulin distribution.

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The effects of exposure to black carbon (BC) on various diseases remains unclear, one reason being potential exposure misclassification following modelling of ambient air pollution levels. Urinary BC particles may be a more precise measure to analyze the health effects of BC. We aimed to assess the risk of prediabetes and metabolic syndrome (MetS) in relation to urinary BC particles and ambient BC and to compare their associations in 5453 children from IDEFICS/I.

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Objective: To investigate whether Swedish men living with children had elevated risk for severe COVID-19 or infection with SARS-CoV-2 during the first three waves of the pandemic.

Design: Prospective registry-based cohort study.

Participants: 1 557 061 Swedish men undergoing military conscription between 1968 and 2005 at a mean age of 18.

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Article Synopsis
  • Living in single-parent and blended families or as an only child is linked to a higher body mass index (BMI) compared to children from two-parent families or those with siblings.
  • Cross-sectional analyses show that having more siblings correlates with lower BMI and better metabolic health, whereas only children have higher BMI over time.
  • The study suggests that obesity prevention efforts should specifically target single-parent households and families without siblings.
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Objective: Overweight and obesity have been identified as risk factors for severe COVID-19; however, prospective cohort studies investigating the association between overweight early in life and severity of COVID-19 are lacking.

Methods: This study included 1,551,670 Swedish men, born between 1950 and 1987, with BMI registered at age 18 years. They were followed until January 9, 2021.

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Purpose: To examine whether positive associations between alcohol and liver enzymes were modified by coffee consumption, smoking, or weight status in a female population.

Methods: Regular consumption of beer, wine, and spirits was assessed in a representative cohort of 1462 Swedish women aged 38-60 in 1968, and re-assessed in 1974. In 1980, gamma-glutamyltransferase (GGT) and aspartase transaminase (AST) were measured in 1130 women.

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Background: Many genes and molecular pathways are associated with obesity, but the mechanisms from genes to obesity are less well known. Eating behaviors represent a plausible pathway, but because the relationships of eating behaviors and obesity may be bi-directional, it remains challenging to resolve the underlying pathways. A longitudinal approach is needed to assess the contribution of genetic risk during the development of obesity in childhood.

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Objective: To examine height changes in middle-aged northern European women in relation to overall and cardiovascular mortality.

Design: Population-based cohort studies with longitudinally measured heights and register-based mortality.

Setting: Sweden and Denmark.

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Objective: To investigate the possible connection between cardiorespiratory fitness (CRF) and muscle strength in early adulthood and severity of COVID-19 later in life.

Design: Prospective registry-based cohort study.

Participants: 1 559 187 Swedish men, undergoing military conscription between 1968 and 2005 at a mean age of 18.

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Background: Despite the high prevalence and severe consequences for health and wellbeing, epidemiological research of neglected emotional needs during childhood is scarce and little is known about its relation to parental socioeconomic position (SEP). This study investigates the prevalence of family violence and parental unavailability in childhood and its association with parental SEP and parental psychological problems in four strata of young Swedish women examined 1990, 1995, 2000, and 2013.

Method: The sample comprised 976 women (mean age 22, range 20-25) living in Sweden.

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Background: The World Health Organization Disability Assessment Schedule 2.0 (WHODAS-2.0) is a self-administered instrument to assess functional impairment.

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Objective: To evaluate the implementation of a care manager organisation for common mental disorders and its association with antidepressant medication patterns on primary care centre (PCC) level, compared with PCCs without this organisation. Moreover, to determine whether a care manager organisation is associated with antidepressant medication patterns that is more in accordance with treatment guidelines.

Design: Register-based study on PCC level.

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