Comparative study of X-ray treatment and photodynamic therapy by using 5-aminolevulinic acid conjugated gold nanoparticles in a melanoma cell line.

Purpose: The most important challenges in photodynamic therapy (PDT) are related to the limited penetration of light and the low uptake of photosensitizers. In radiotherapy, they are correlated to radiation damage of normal tissues. Therefore, a targeted radio and photosensitizer can reduce the limitations of the mentioned methods.

The Stromal Overexpression of CD10 in Invasive Breast Cancer and its Association with Clincophathologic Factors.

Background: Breast carcinoma is the most common non-skin malignancy in women. More recently, it has been suggested that extracellular proteinase has also regulated growth factors and cytokines that might contribute to tumor progression. CD10 is a 90-110kd cell surface zinc-dependent metalloproteinase.

Correlation of serum and salivary CA125 levels in patients with breast cancer.

Aim: The aim of this study was to examine the relationship between serum and saliva levels of cancer antigen (CA) 125 and compare them among healthy women and patients with treated and untreated breast cancer.

Methods And Materials: CA125 levels were assayed in serum and unstimulated whole saliva of 25 normal healthy women, 24 patients with untreated breast cancer, and 23 patients with treated breast cancer using enzyme immunoassay (EIA) kits.

Results: The mean saliva and serum CA125 levels were significantly higher in untreated cancer women compared to healthy and treated groups.

Expression of p53 in colorectal carcinoma: correlation with clinicopathologic features.

Background: The p53 gene mutation is closely related to carcinogenesis in most malignant diseases. The main function of wild p53 protein is to maintain the integrity of genes by detecting mutations and preventing the division of cells with damaged DNA. The mutated form of p53 protein is overexpressed due to an extended half-life and can be easily detected by immunohistochemistry.