Publications by authors named "Mehdi Safaeizadeh"

Article Synopsis
  • This research utilized high-throughput RNA sequencing (RNA-Seq) to analyze how wild-type Arabidopsis seedlings respond to two different peptide elicitors: AtPep1 (a damage-associated molecular pattern) and flg22 (a microbe-associated molecular pattern).
  • The study identified 256 genes uniquely up-regulated by flg22 and 328 genes uniquely up-regulated by AtPep1, highlighting distinct genetic responses to these stimuli, as well as shared responses.
  • Key genes related to innate immunity were characterized, revealing that pp2-b13 and aclp1 mutants were more susceptible to Pseudomonas syringae infections, with aclp1 showing reduced ethylene production and pp2-b13 showing deficits in reactive
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In innate immunity, the first layer of defense against any microbial infection is triggered by the perception of pathogen-associated molecular patterns by highly specific pattern recognition receptors. The and are plant-pathogenic bacterial species that include pathogenic strains in a wide range of different plant species. In the current study, extensive analysis including gene expression of 12 hub genes, gene ontology, protein-protein interaction, and cis-element prediction to dissect the response to above-mentioned bacteria were performed.

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In Arabidopsis thaliana AtPEPR1 and AtPEPR2 act as the receptors for the endogenous AtPROPEP-derived Pep peptides and subsequently initiate defense-signaling cascades. In the previous work, the expression pattern of the genes encoding the PEPR receptors and the AtPROPEP peptide precursor proteins was studied using promoter-GUS reporter constructs. Here, using the same constructs to study their expression pattern under biotic and abiotic stress, including AtPep1, flg22, methyl jasmonate (MeJA), and NaCl treatments, we observed that in response to AtPep1 and flg22, the activation of AtPEPR1 promoter was different from AtPEPR2.

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