Changes in Growth and Metabolic Profile of Georgi in Response to Sodium Chloride.

Georgi is a valuable medicinal plant of the family. Its roots have been used in Traditional Chinese Medicine (under the name Huang-qin) since antiquity and are nowadays included in Chinese and European Pharmacopoeias. It is abundant in bioactive compounds which constitute up to 20% of dried root mass.

Chemical Composition, Physiological and Morphological Variations in subg. Populations in Response to Different Salinity Levels.

This study evaluated the salinity tolerance of five populations of subg. ( and ). The aims of the study were to assess essential oil components, as well as growth and physiological parameters of two species in response to salt stress.

Changes in Morphological, Physiological and Phytochemical Traits of Different Dill ( L.) Cultivars as Affected by Light-Emitting Diodes.

Dill is a fragrant vegetable containing various beneficial compounds for health. This research aims to evaluate the impact of various spectra of LED light on essential oil composition and morphological and physiological characteristics of three dill cultivars. LED light treatments included greenhouse light as control (C), blue (B), red (R), red + blue (RB), and white (W).

Effect of Physical Treatments on Functional Properties of Whey and Soy Protein Isolates in Oleogel Production Through Foam Template Method.

This study aimed to investigate the impact of physical treatments, namely heat (70 °C for 48 h), atmospheric cold plasma (10 kW for 20 min), and ultrasonic frequency (40 kHz for 15 min), on the physicochemical and interfacial properties of soy protein isolate (SPI) and whey protein isolate (WPI) in the context of oleogel production by foam template (cryogel) method. The physical modification of both SPI and WPI was monitored using SDS-PAGE, Fourier transform infrared spectroscopy (FTIR) spectroscopy, and differential scanning calorimetry (DSC), measuring interfacial tension, color, solubility, foam volume, foam stability, and, finally, the density and oil absorption of the produced cryogel. The findings revealed that the application of ultrasonic waves resulted in a significant reduction in the content of alpha-helical of SPI and WPI while the other treatments increased the content of random coil proteins.

Evaluation of Different Drying Treatments with Respect to Essential Oil Components, Phenolic and Flavonoid Compounds, and Antioxidant Capacity of Ajowan ( L.).

Ajowan ( L.) is considered a valuable spice and medicinal herb. In this study, the essential oil content and composition of the aerial parts of ajowan were investigated under different drying treatments (sun, shade, oven at 45 °C, oven at 65 °C, microwave, and freeze drying).

The relation between apomictic seed production and morpho-physiological characteristics in a world collection of castor bean (Ricinus communis L.).

Ricinus communis is one of the most important oilseed plants with many medicinal and industrial applications. Variation in 30 genotypes of castor bean collected from different regions of the world was evaluated for two consecutive years and the difference in seed production with two different reproductive modes (including apomixis and open-pollination) was compared based on yield components, agronomic traits, and phytochemical properties. Results of data analysis demonstrated that castor bean has the ability for a wide range of apomixis for seed production and the highest percentages of apomixis ability in the first and second years were 86.

Fabrication and characterization of pectin-zein nanoparticles containing tanshinone using anti-solvent precipitation method.

Tanshinone compounds are secondary metabolites which their application in food and pharmaceutical industry is limited due to the low solubility in water and sensitivity to heat. This study aimed to develop a novel biopolymer nanocarriers system based on pectin/zein for the encapsulation of tanshinone compounds using the anti-solvent precipitation method. The concentration of pectin and mass ratio of tanshinone/zein in the final formulation of nanoparticles were optimized.

Screening some pine species from North America and dried zones of western Asia for drought stress tolerance in terms of nutrients status, biochemical and physiological characteristics.

Drought due to climate change or reduced precipitation is one of the main factors limiting the growth and establishment of plants and is one of the most critical challenges facing humans. To investigate the effect of different levels of drought stress on some pine species, this research was carried out as a factorial experiment using two factors and a completely randomized design. It included five populations of four pine species ( Ten.

Induces Cancer Cell Death in Breast and Glioblastoma Cancer in 2D/3D Models and Suppresses Breast Cancer Stem Cells.

Overcoming drug resistance and specifically targeting cancer stem cells (CSCs) are critical challenges in improving cancer therapy. Nowadays, the use of novel and native medicinal plants can provide new sources for further investigations for this purpose. The aim of this study was to assess the potential of , an endemic plant with diverse medicinal applications, in suppressing and targeting cancer and cancer stem cells in glioblastoma and breast cancer.

Metabolic and Transcriptomic Approaches of Chitosan and Water Stress on Polyphenolic and Terpenoid Components and Gene Expression in (Karl.) and .

In this research, a HPLC analysis, along with transcriptomics tools, was applied to evaluate chitosan and water stress for the prediction of phenolic flavonoids patterns and terpenoid components accumulation in Karel and . The results indicated that the tanshinone contents under drought stress conditions increased 4.2-fold with increasing drought stress intensity in both species.

Chemical Investigations in Mozaff. Leaves Based on Comprehensive Analytical Methods: LC-MS, SPME, and GC-MS Analyses.

Mozaff. is a species of Apiaceae endemic to the Zagros Mountains in Iran. In the present investigation, for the first time, the polyphenolic compounds and flavonoids of its leaves were determined by liquid chromatography-mass spectrometry (LC-MS).

Phytochemical, Morphological, and Physiological Variation in Different Ajowan ( L.) Populations as Affected by Salt Stress, Genotype × Year Interaction and Pollination System.

In the present research, 28 populations of ajowan ( L.) were evaluated for agro-morphological traits and essential oil yield in two consecutive years. Then, selected ajowan populations from these two years were used for further morphophysiological and biochemical studies under different salinity levels (control, 60, 90, and 120 mM NaCl).

Identification of Polyphenolic Compounds Responsible for Antioxidant, Anti- Activities and Nutritional Properties in Different Pistachio ( L.) Hull Cultivars.

The use of by-products from the agri-food industry is a promising approach for production of value-added, polyphenol-rich dietary supplements or natural pharmaceutical preparations. During pistachio nut processing, a great amount of husk is removed, leaving large biomass for potential re-use. The present study compares antiglycative, antioxidant, and antifungal activities as well as nutritional values of 12 genotypes belonging to four pistachio cultivars.

Essential Oil Composition and Antioxidant Activity of Oregano and Marjoram as Affected by Different Light-Emitting Diodes.

Oregano and marjoram are important aromatic spices in the food industry, as well as medicinal plants with remarkable antioxidant properties. Despite their popularity, little is known about treatments that would influence the antioxidant capacity of essential oils. In this study, different spectra of LED light, namely blue, red, white, blue-red, and natural ambient light as a control, were applied to assess the essential oil content, composition, flavonoid, phenolic, and antioxidant capacity of oregano and marjoram.

Mycorrhizal Colonization Modulates the Essential Oil Profile and Enzymatic and Non-Enzymatic Antioxidants to Mitigate the Adverse Effects of Water Deficit in subg. .

Among traditional Iranian herbs, species (a subgenus of ), while being valued ornamentals, are also studied for numerous potential pharmacological and therapeutic aspects. The current study was conducted to assess the effectiveness of two species of arbuscular mycorrhizal fungi (AMF), and separately and in combination, in terms of the essential oil content and compositions along with the enzymatic and non-enzymatic antioxidants in and in response to three levels of irrigation, including 100% FC as well-watered, 75% FC (moderate irrigation deficit), and 50% FC (severe irrigation deficit). In both species, essential oil content, enzyme antioxidant activities, total phenolics, and flavonoids were increased significantly with the severity of stress; this increase was more pronounced in mycorrhizal inoculated herbs.

Metabolic and physiological effects of water stress on Moshgak (Ducrosia anethifolia Boiss) populations using GC-MS and multivariate analyses.

Ducrosia anethifolia Boiss is a medicinal and aromatic plant that is used as a food additive and drug in the areas of natural distribution. In this study, eight populations from different geographical regions of Iran were evaluated for their essential oil composition, total phenolics and flavonoids as well as for free radical scavenging activity during two consecutive years under water deficit. Analysis of variance was performed using a randomized block design at three levels of irrigation and 2 years, using the GLM procedure of SAS software and cluster analysis was used according to Ward's method using squared Euclidean dissimilarity.

Changes in polyphenolic composition, physiological characteristics, and yield-related traits of Moshgak (Ducrosia anethifolia Boiss.) populations in response to drought stress.

Ducrosia anethifolia (DC.) Boiss. is an aromatic medicinal plant that has been traditionally used as an analgesic to treat headaches, backaches, colic, and cold.

Changes in Essential Oil Composition, Polyphenolic Compounds and Antioxidant Capacity of Ajowan ( L.) Populations in Response to Water Deficit.

Ajowan ( L.) is considered a valuable spice plant with a high thymol content. Seed yield, essential oil constituents, polyphenolic composition, and antioxidant capacity of ajowan ( L.

Morpho-Physiological and Molecular Characterization Reveal Low Genetic Variation for Conservation of Endangered Iranian Moshgak (Ducrosia anethifolia Boiss).

Ducrosia anethifolia Boiss is an aromatic vegetable and medicinal plant of Apiaceae family. In this study, morphological and essential oil studies as well as ISSR analyses were employed to investigate genetic diversity in 120 Moshgak accessions of 24 Iranian populations. High variations were observed in morpho-physiological traits (morphological and essential oil contents) of the populations in 2 consecutive agronomic years.

Physiological and Transcriptome Indicators of Salt Tolerance in Wild and Cultivated Barley.

Barley is used as a model cereal to decipher salt tolerance mechanisms due to its simpler genome than wheat and enhanced salt tolerance compared to rice and wheat. In the present study, RNA-Seq based transcriptomic profiles were compared between salt-tolerant wild (, genotype no. 395) genotype and salt-sensitive cultivated (, 'Mona' cultivar) subjected to salt stress (300 mM NaCl) and control (0 mM NaCl) conditions.

Anticancer drug discovery from Iranian Chrysanthemum cultivars through system pharmacology exploration and experimental validation.

Breast cancer is the most common carcinoma in women, and natural products would be effective preventing some side effects of cancer treatment. In the present study, cytotoxic activities of different Iranian Chrysanthemum morifolium cultivars were evaluated in human breast cancer cell lines (MCF-7) and human lymphocytes. A systems pharmacology approach was employed between major compounds of these cultivars (chlorogenic acid, luteolin, quercetin, rutin, ferulic acid, and apigenin) and known breast cancer drugs (tucatinib, methotrexate, tamoxifen, and mitomycin) with 22 breast cancer-related targets to analyze the mechanism through which Chrysanthemum cultivars act on breast cancer.

Seasonal Variations of Rosmarinic Acid and Its Glucoside and Expression of Genes Related to Their Biosynthesis in Two Medicinal and Aromatic Species of subg. .

Kar. and B.T.