Synthesis of furan-2-ones and spiro[furan-2,3'-indoline] derivatives using polyether sulfone sulfamic acid catalysis.

Polyether sulfone sulfamic acid (PES-NHSOH) was prepared by simple sulfonation of a modified polyether sulfone. The number of acidic sites (SOH) was determined to be 4.23 mmol H/g by acid-base titration and 4.

Alkyl ammonium hydrogen sulfate immobilized on FeO@SiO nanoparticles: a highly efficient catalyst for the multi-component preparation of novel tetrazolo[1,5-a]pyrimidine-6-carboxamide derivatives.

In this, a three-component reaction for the preparation of novel tetrazolo[1,5-a]pyrimidine-6-carboxamide derivatives from N,N'-(sulfonylbis(1,4-phenylene))bis(3-oxobutanamide), aldehydes and 1H-tetrazol-5-amine is reported. The application of FeO@SiO-(PP)(HSO) (A) as a catalyst afforded the desired products (a-a) in high yields in DMF as solvent as well as under solvent-free conditions.

Multi-Component Syntheses of Spiro[furan-2,3'-indoline]-3-carboxylate Derivatives Using Ionic Liquid Catalysts.

Two previously described Brønsted acidic ionic liquids, 3,3'-(1,6-hexanediyl)bis(1-methyl)-1-imidazolium hydrogen sulfate () and 1,1'-(1,6-hexanediyl)bis(pyridinium) hydrogen sulfate (), were used as catalysts for the preparation of spiro[furan-2,3'-indoline]-3-carboxylate derivatives via a three-component reaction of anilines, isatins (-alkyl-indoline-2,3-diones), and diethyl acetylenedicarboxylate, in high yields. The use of ultrasonic (US) irradiation led to the targeted products (-) in high yields ranging from 80% to 98%. Under the same conditions, the use of sulfuric acid and acetic acid as a Brønstedt catalyst did not yield the desired benchmark product .

Polyethylenimine Grafted onto Nano-NiFeO@SiO for the Removal of CrO, Ni, and Pb Ions from Aqueous Solutions.

Polyethyleneimine (PEI) has been reported to have good potential for the adsorption of metal ions. In this work, PEI was covalently bound to NiFeO@SiO nanoparticles to form the new adsorbent NiFeO@SiO-PEI. The material allowed for magnetic separation and was characterized via powder X-ray diffraction (PXRD), showing the pattern of the NiFeO core and an amorphous shell.

A Sulfonic Acid Polyvinyl Pyridinium Ionic Liquid Catalyzes the Multi-Component Synthesis of Spiro-indoline-3,5'-pyrano[2,3-]-pyrimidines and -Pyrazines.

A sulfonated poly-4-vinyl pyridinium (PVPy-IL-B-SOH) containing an acidic pyridinium/HSO ionic liquid moiety was prepared and used as a catalyst for the three-component reaction of malononitrile with 1-alkylindoline-2,3-diones and 1,3-dimethylpyrimidine-2,4,6(1,3,5)-trione or methyl 5-hydroxy-1-pyrazole-3-carboxylate, leading to methyl 6'-amino-5'-cyano-2-oxo-2'-spiro[indoline-3,4'-pyrano[2,3-]pyrazole]-3'-carboxylates or -3,4'-pyrano[2,3-]pyrimidine]-6'-carbonitrile derivatives under ultrasonic irradiation conditions. The solid catalyst allows easy separation, is cheap, produces high yields under mild conditions, and does not require column chromatography for product isolation and purification.

A Cu(ii) complex supported on FeO@SiO as a magnetic heterogeneous catalyst for the reduction of environmental pollutants.

Today, the presence of pollutants in the environment has become one of the serious problems and concerns of human beings. To eliminate these pollutants, researchers have made many efforts. One of the most important of these efforts is the reduction of such contaminants in the presence of effective catalysts.

Molecular dynamics simulation of drug delivery across the cell membrane by applying gold nanoparticle carrier: Flutamide as hydrophobic and glutathione as hydrophilic drugs as the case studies.

In this study, molecular dynamics simulation is applied to investigate drug transport in both pure state and conjugated with neutral gold nanoparticle (AuNP) as a drug carrier inside dipalmitoylphosphatidylcholine (DPPC) membrane. Flutamide (Flu) as a hydrophobic and Glutathione (GSH) as a hydrophilic anticancer drug are selected as the case studies. Dynamics of each drug including adhesion on and penetration into the cell membrane are investigated.

Evolutionary and Ecological Drivers Shape the Emergence and Extinction of Foot-and-Mouth Disease Virus Lineages.

Livestock farming across the world is constantly threatened by the evolutionary turnover of foot-and-mouth disease virus (FMDV) strains in endemic systems, the underlying dynamics of which remain to be elucidated. Here, we map the eco-evolutionary landscape of cocirculating FMDV lineages within an important endemic virus pool encompassing Western, Central, and parts of Southern Asia, reconstructing the evolutionary history and spatial dynamics over the last 20 years that shape the current epidemiological situation. We demonstrate that new FMDV variants periodically emerge from Southern Asia, precipitating waves of virus incursions that systematically travel in a westerly direction.

Platinum(II) complex with 4-nitro-N-(pyridin-2-ylmethylidene)aniline: synthesis, characterization, crystal structure and antioxidant activity.

A novel complex has been prepared using the (E)-4-nitro-N-(pyridin-2-ylmethylidene)aniline bidentate Schiff base ligand and PtCl, namely, dichlorido[(E)-4-nitro-N-(pyridin-2-ylmethylidene)aniline-κN,N']platinum(II) acetonitrile hemisolvate, [PtCl(CHNO)]·0.5CHCN, 1. According to the X-ray measurements of the crystal structure, the Pt ion adopts a PtClN square-planar coordination.

Mannich bases derived from lawsone and their metal complexes: synthetic strategies and biological properties.

Lawsone (2-hydroxynaphthalene-1,4-dione) is a natural product which shows significant biological activity. Aminomethylnaphthoquinone Mannich bases derived from lawsone constitute an interesting class of naphthoquinones and/or their metal complexes have demonstrated a series of important biological properties. So, this review aimed to document the publications concerning the synthesis of aminomethylnaphthoquinone Mannich bases from lowsone, aldehydes and amines and their metal complexes using different conditions, and investigation of their applications.

Domino ring opening/cyclization of oxiranes for synthesis of functionalized 2H-pyran-5-carboxylate.

A simple method for the synthesis of functionalized 2H-pyrans via a catalytic reaction of an oxirane, an alkyne, and a malonate has been developed in which a 6-exo-dig cyclization pathway is observed. In this transformation, the attack of in situ generated copper acetylides on oxiranes formed homopropargylic alcohol intermediates which further transferred to 2H-pyrans with the help of malonates.

Natrolite zeolite supported copper nanoparticles as an efficient heterogeneous catalyst for the 1,3-diploar cycloaddition and cyanation of aryl iodides under ligand-free conditions.

In this paper, we report the preparation of Natrolite zeolite supported copper nanoparticles as a heterogeneous catalyst for 1,3-diploar cycloaddition and synthesis aryl nitriles from aryl iodides under ligand-free conditions. The catalyst was characterized using XRD, SEM, TEM, EDS and TG-DTA. The experimental procedure is simple, the products are formed in high yields and the catalyst can be recycled and reused several times without any significant loss of catalytic activity.

Diiodido{2-[(4-meth-oxy-phen-yl)imino-meth-yl]pyridine-κ(2)N,N'}zinc.

In the title complex, [ZnI(2)(C(13)H(12)N(2)O)], the Zn(II) atom has a distorted tetra-hedral coordination. The organic ligand is bidentate, coordinating the Zn(II) atom via the two N atoms. The benzene and pyridine rings are oriented at a dihedral angle of 11.

A second monoclinic polymorph of di-μ-chlorido-bis-(chlorido{2-[(4-ethyl-phen-yl)imino-meth-yl]pyridine-κ²N,N'}copper(II)).

The title compound, [Cu₂Cl₄(C₁₄H₁₄N₂)₂], is a new polymorph of a previously reported compound [Dehghanpour et al. (2011 ▶). Acta Cryst.

Aqua-[tris-(2-{5-[(4-methyl-phenyl)diazen-yl]-2-oxidobenzyl-idene-amino}-eth-yl)amine]-samarium(III) acetonitrile monosolvate.

In the title compound, [Sm(C(48)H(45)N(10)O(3))(H(2)O)]·CH(3)CN, the Sm(III) ion is coordinated by the hepta-dentate tris-(2-{5-[(4-methyl-pheny)diazen-yl]-2-oxidobenzyl-idene-amino}-eth-yl)amine trianionic ligand and a water mol-ecule. The resulting SmN(4)O(4) coordination polyhedron is a distorted square anti-prism. In the crystal, complex mol-ecules are linked by O-H⋯O hydrogen bonds.

Dichlorido{2-[(3,4-dimethyl-phen-yl)imino-meth-yl]pyridine-κN,N'}copper(II).

In the title complex, [CuCl(2)(C(14)H(14)N(2))], the Cu(II) atom exhibits a very distorted tetra-hedral coordination geometry involving two chloride ions and two N-atom donors from the Schiff base ligand. The range for the six bond angles about the Cu(2+) cation is 81.49 (11)-145.

Dibromido{2-[(4-nitro-phen-yl)imino-meth-yl]pyridine-κN,N'}zinc(II).

In the title compound, [ZnBr(2)(C(12)H(9)N(3)O(2))], the Zn(II) ion is bonded to two Br ions and two N atoms of the diimine ligand in a distorted tetra-hedral geometry. With the exception of the Br atoms, all other atoms are disordered over two sets of sites corresponding to a 180° rotation of the mol-ecule along [[Formula: see text]02]. The refined occupancies of the components are 0.

Di-μ-chlorido-bis-(chlorido{2-[(4-ethyl-phen-yl)imino-meth-yl]pyridine-κN,N'}copper(II)).

The binuclear title complex, [Cu(2)Cl(4)(C(14)H(14)N(2))(2)], is located on a crystallographic inversion centre. The Cu(II) ion is in a distorted square-pyramid coordination environment formed by the bichelating N-heterocyclic ligand, two bridging Cl atoms and one terminal Cl atom. One of the bridging Cu-Cl bonds is significantly longer than the other.

2-[1-(3-{2-[(2-Hy-droxy-benzyl-idene)amino]-phen-oxy}prop-yl)-1H-1,3-benzodiazol-2-yl]phenol.

In the title compound, C(29)H(25)N(3)O(3), the imine double bond has an E configuration. The dihedral angle between the hy-droxy-phenyl and benzene rings in the imine moiety is 26.95 (9)°, and the dihedral angle between the hy-droxy-phenyl and benzimidazole rings in the other moiety is 14.

Zwitterionic form of tris-({[5-(4-meth-oxy-phenyl-azo)salicyl-idene]amino}-eth-yl)amine.

2-{[2-(bis-{2-[({2-hy-droxy-5-[(4-meth-oxy-phen-yl)diazen-yl]phen-yl}methyl-idene)amino]-eth-yl}amino)-eth-yl]aza-niumylidenemeth-yl}-4-[(4-meth-oxy-phen-yl)diazen-yl]phenolate), C(48)H(48)N(10)O(6), exists as a zwitterion in the solid state. The three arms of the tripodal mol-ecule are located close to each other and an intra-molecular hydrogen bond occurs in each arm (O-H⋯N in two arms and N-H⋯O in the zwitterionic arm). The dihedral angles between the aromatic rings in the three arms are 16.

Di-μ-chlorido-bis-{chlorido[4-nitro-N-(pyridin-2-yl-methyl-idene-κN)aniline-κN]mercury(II)}.

In the centrosymmetric dinuclear title complex, [Hg(2)Cl(4)(C(12)H(9)N(3)O(2))(2)], the Hg(II) ion is in a distorted square-pyramidal coordination environment formed by the N atoms of the diimine ligand, two bridging Cl atoms and one terminal Cl atom. One of the bridging Hg-Cl bonds is significantly longer than the other.

Bromidotricarbon-yl[4-chloro-N-(2-pyridyl-methyl-idene)aniline-κN,N']rhenium(I).

In the title compound, [ReBr(C(12)H(9)ClN(2))(CO)(3)], the Re(I) atom has a distorted octa-hedral configuration with the three carbonyl ligands showing a facial arrangement. The main distortion of the octa-hedron is due to a small bite angle of the chelating bidentate diimine ligand [N-Re-N = 75.3 (3)°].

Dichlorido{2-[(4-iodo-phen-yl)imino-meth-yl]pyridine-κN,N'}copper(II).

The Cu(II) atom in the title complex, [CuCl(2)(C(12)H(9)IN(2))], has a square-planar coordination being N,N'-chelated by the Schiff base ligand, and by two Cl atoms. The geometry is distorted towards square pyramidal owing to a long Cu⋯Cl inter-action of 2.941 (1) Å.

Dibromido{2-[(4-bromo-phen-yl)imino-meth-yl]pyridine-κN,N'}zinc(II).

In the title complex, [ZnBr(2)(C(12)H(9)BrN(2))], the Zn(II) ion is in a distorted tetra-hedral coordination environment formed by two imine N atoms of the bis-chelating N-heterocyclic ligand and two Br atoms. The dihedral angle between the pyridine and benzene rings is 8.04 (17)°.

Di-μ-chlorido-bis-({2-[(4-bromo-phen-yl)-imino-meth-yl]pyridine-κN,N'}-chloridomercury(II)).

The unique Hg(II) ion in the title centrosymmetric dinuclear complex, [Hg(2)Cl(4)(C(12)H(9)BrN(2))(2)], is in a distorted trigonal-bipyramidal coordination environment formed by the bis-chelating N-heterocyclic ligand, two bridging Cl atoms and one terminal Cl atom. One of the bridging Hg-Cl bonds is significantly longer than the other.