Integration of Porous Nanomaterial-Infused Membrane in UF/FO Membrane Hybrid for Simulated Osmosis Membrane Bioreactor (OsMBR) Process.

This study explored the use of a combination of hydrothermal and sol-gel methods to produce porous titanium dioxide (PTi) powder with a high specific surface area of 112.84 m/g. The PTi powder was utilized as a filler in the fabrication of ultrafiltration nanocomposite membranes using polysulfone (PSf) as the polymer.

Conjugation of folic acid with poly (NVCL-co-PEGMA)-grafted chitosan as a new doxorubicin delivery system.

This paper aimed to investigate the synthesis of a novel drug delivery system (DDS) to target tumors and implement the controlled release of doxorubicin (DOX). Chitosan was modified with 3-mercaptopropyltrimethoxysilane and subjected to graft polymerization to implement grafting with the biocompatible thermosensitive copolymer of poly (NVCL-co-PEGMA). A folate receptor-targeting agent was obtained by attaching folic acid.

pH-responsive glycodendrimer as a new active targeting agent for doxorubicin delivery.

The present study synthesized a new kind of pH-responsive active targeting glycodendrimer (ATGD) for doxorubicin delivery to cancerous cells. First, the glycodendrimer was synthesized based on the cultivation of chitosan dendrons on amine-functionalized, silica-grafted cellulose nanocrystals. Afterward, glycodendrimer was conjugated with folic acid to provide a folate receptor-targeting agent.

Synthesis of thermosensitive magnetic nanocarrier for controlled sorafenib delivery.

Allyl glycidyl ether/N-isopropylacrylamide-grafted magnetic nanoparticles were prepared using silica-coated magnetic nanoparticles as a substrate for radical copolymerization of allyl glycidyl ether and N-isopropylacrylamide. Chitosan was coupled with the prepared nanoparticles by opening the epoxy ring of the allyl glycidyl ether. The thermosensitive magnetic nanocarrier (TSMNC) obtained can be applied as a potent drug carrier.