The accumulation of nisin in the fermentation medium can reduce the process's productivity. This research studied the potential of Nymphaea alba leaf powder (NALP) as a hydrophobic biosorbent for efficient in-situ nisin adsorption from the fermentation medium by docking and experimental analysis. Molecular docking analysis showed that di-galloyl ellagic acid, a phytochemical compound found in N.
View Article and Find Full Text PDFThe objective of this study focused on the design and preparation of a molecularly modified polycarboxylate superplasticizer to develop concretes with enhanced engineering features. For this purpose, polyethylene glycol was chemically modified with maleic anhydride to give the mono polyethylene glycol maleate (MPEGM). Then, polycarboxylate superplasticizer comprising of isoprenyl oxy polyethylene glycol (TPEG) and acrylic acid (AA, PCE-1), and the synthesized MPEGM with TPEG and AA (PCE-2) were prepared through solution radical polymerization.
View Article and Find Full Text PDFBackground: Glycyrrhizic Acid (GA), a compound derived from licorice, has exhibited promising anticancer properties against several cancer types, including Prostate Cancer (PCa) and Gastric Cancer (GCa).
Objective: This study has introduced a novel approach involving the encapsulation of GA and Licorice extract (Lic) into Polyethylene Glycol Liposomes (PEG-Lip) and assessed their efficacy against AGS (human gastric cancer) and PC-3 (human prostate cancer) cells, marking the first report of this endeavor.
Methods: We synthesized GA-loaded PEG-Lip (GA PEG-Lip) and Lic-loaded PEG-Lip (Lic PEG-Lip) through the reverse-phase evaporation method.
This study investigates the utilization of an α-MnO/nanocarbon ball (NCB) additive to enhance the performance of second-, third-, and fourth-generation biodiesels (SSGB, PVB, and GMCB). Various tests including XRD, XPS, TEM, HRTEM, BET, torque and power measurements, EGT, BTE, emissions analysis (CO, CO, HC, soot, and NOx), and BSFC were conducted. The combination of GMCB5N50 with α-MnO/NCB yielded the highest torque (35.
View Article and Find Full Text PDFThe sea contains elements that can play a useful role in catalyzing reactions. Therefore, this research was done to focus on eliminating amoxicillin (AMX) from wastewater utilizing zeolite Y- sea salt catalyst in the presence of HO. The influences of furnace temperature (200-500 °C) and time duration in the furnace (1-4 h) were optimized during catalyst generation.
View Article and Find Full Text PDFIn this study the adsorption properties of the doxorubicin anticancer drug on the designed and fabricated system is investigated. A novel nanocomposite based on green magnetic - Graphene Oxide - Chitosan - Allium Sativum- Quercus was successfully fabricated. To evaluate of the doxorubicin adsorption the effectiveness parameters on the adsorption process containing the contact time, pH value, concentration, the adsorbent dosage, and temperature were investigated.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
August 2021
One of the most prominent features of selective catalytic reduction (SCR) of NO is using a well-structured catalyst to advance the reaction in a desirable condition. At the present work, various crystal structures of Fe-Mn nanocatalysts, FeMnO spinel, FeMnO perovskite and FeO (hematite)/MnO (bixbyite) nanocatalysts fabricated by co-precipitation method were evaluated for selective catalytic reduction of NO by NH (NH-SCR). The studies specified that the crystal structure type had a high impact on structural properties and thereby the catalytic performance of the samples.
View Article and Find Full Text PDFIn this paper, Zeolite-MgO was generated using alkali-thermal method and was utilized as a catalyst to decrease amoxicillin (AMX) concentration in the presence of HO from wastewater. Different tests like Fourier-transform infrared (FTIR), Brunauer-Emmett-Teller (BET), field emission scanning electron microscopy-energy dispersive X-ray analysis (FESEM-EDX), thermogravimetric analysis (TGA), and X-ray diffraction (XRD) were done to determine catalyst properties. Active groups of C-S-C, CO, CC, C-N, C-O, N-O, and N-H were identified in catalyst frame.
View Article and Find Full Text PDFDrilling cuttings contain dangerous elements to human life and other organisms. Different criteria are effective in increasing or decreasing the transmission of this pollution to the environment. By studying and reviewing the scientific sources, these criteria were identified and the type of causal relationships between these criteria was determined using the Fuzzy DEMATEL technique.
View Article and Find Full Text PDFWith the global epidemic of the COVID-19 virus, extensive and rapid research on drug therapy is underway around the world. In this regard, one of the most widely studied drugs is Favipiravir. Our aim in this paper is to conduct comprehensive research based on the Density Functional Theory (DFT) on the potential of metallofullerenes as suitable drug carriers.
View Article and Find Full Text PDFBackground: Drug delivery systems have demonstrated promising results to cross blood-brain barrier (BBB) and deliver the loaded therapeutics to the brain tumor. This study aims to utilize the transferrin receptor (TR)-targeted liposomal cisplatin (Cispt) for transporting Cispt across the BBB and deliver Cispt to the brain tumor.
Methods: Targeted pegylated liposomal cisplatin (TPL-Cispt) was synthesized using reverse phase evaporation method and thiolated OX26 monoclonal antibody.
Fascioliasis is an important neglected tropical disease that causes severe injury to the bile ducts and liver. Therefore, a rapid and accurate method for detection of Fasciola hepatica infection plays a vital role in early treatment. Currently, the diagnosis of fascioliasis is mainly conducted via serological tests using the excretory/secretory (E/S) products, which might cross-react with antigens from other helminth parasitic diseases.
View Article and Find Full Text PDFThe present study is an attempt to examine the effect of biodiesel chemical structure on the diesel engine combustion properties and exhaust emissions. For this purpose, nine new types of oil (second generation) are used for producing biodiesel. Also, fatty acid profiles are determined by gas chromatography.
View Article and Find Full Text PDFCardiovascular diseases are a leading cause of death. Vascular surgery is mainly used to solve this problem. However, the generation of a functional and suitable substitute for small diameter (< 6 mm) displacement is challengeable.
View Article and Find Full Text PDFWaste from drilling operations of oil and gas wells in the event of poor management, in addition to imposing costs, can lead to environmental problems. This research was aimed at providing a suitable model for collecting, transferring, and recycling the drilling wastes produced in the operational areas of the Iranian offshore oil company. Data analysis was performed using the Expert Choice and template selection using the analytical hierarchy process method.
View Article and Find Full Text PDFBackground: Doxorubicin, as a strong anti-cancer agent for clinical treatment of various cancer types along with other drugs, is widely utilized. Due to the physiology of the human body and cancerous tissues, the applicability of doxorubicin is still limited and the targeted treatment of the different types of cancers is considered. Also, the side effects of the conventional forms of chemotherapy medicines, damaging and stressing the normal cells are considerable.
View Article and Find Full Text PDFArtif Cells Nanomed Biotechnol
December 2019
Lung cancer is the most common one in terms of outbreak and mortality. Since most modern treatments have many side effects, finding an effective and alternative therapy seems necessary. The present study aimed to determine the effect of PEGylated liposomal etoposide nanoparticles on the lung cancer (A-549 and Calu6 cell lines).
View Article and Find Full Text PDFTo determine the optimum condition for the extraction of Hyssopus officinalis L. essential oil (EO) by instant controlled pressure drop (in French: Détente Instantanée Contrôlée or DIC), the influential parameters of pressure, heating time per cycle, number of cycles, mean particle diameter of the herb, and water concentration in the steam generator feed were evaluated using response surface methodology (RSM). The impact of using an ethanol-water mixture to generate the required vapor in the DIC process on EO extraction was investigated.
View Article and Find Full Text PDFThis research has analysed the physiochemical properties of a catalyst that has been developed - biochar-La, including BJH, BET, EDX, SEM, FTIR, pHpzc, and iodine number. The catalyst consisted of effective functional groups, including C=S, C-O, C=C, -COOH and O-H, with a specific surface area of 31.2 m/g.
View Article and Find Full Text PDFPurpose: curcumin is poorly water soluble drug with low bioavailability. Use of lipid systems in lipophilic substances increases solubility and bioavailability of poorly soluble drugs. The aim of this study was to prepare curcumin loaded Solid Lipid Nanoparticles (SLNs) with high loading efficiency, small particle size and prolonged release profile with enhanced antibacterial efficacy.
View Article and Find Full Text PDFCarboxymethyl-curdlan as a water soluble curdlan derivative, was synthesized in an aqueous alkaline medium using monochloroacetic acid. Novel carboxymethyl-curdlan (CC) microspheres were prepared by the method of W/O/W emulsion. The chemical and morphological structures of CC microspheres were investigated by scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR) and particle size analysis.
View Article and Find Full Text PDFA new method was applied to produce modified nanoporous silica as a novel sorbent for Pb(II) ion SPE from industrial wastewater samples. In this modified method, the produced nanoporous silica has a higher functional group loading, which leads to a higher preconcentration factor as well as a lower LOD. This modified nanoporous silica was used for preconcentration prior to subsequent determination of Pb(II) ions by flame atomic absorption spectrometry.
View Article and Find Full Text PDFBackground: There is substantial clinical data supporting the role of Bifidobacterium bifidum in human health particularly in benefiting the immune system and suppressing intestinal infections. Compared to the traditional lyophilization, spray-drying is an economical process for preparing large quantities of viable microorganisms. The technique offers high production rates and low operating costs but is not usually used for drying of substances prone to high temperature.
View Article and Find Full Text PDFPaenibacillus polymyxa ATCC 21830 was used for the production of curdlan gum for first time. A Box-Behnken experimental design was applied to optimize six variables of batch fermentation culture each at three levels. Statistical analyses were employed to investigate the direct and interactive effects of variables on curdlan production.
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