Publications by authors named "Mehboob B Sheikh"

Muscadine grapes are renowned for their unique traits, natural disease resistance, and rich bioactive compounds. Despite extensive research on their phytochemical properties, microbial communities, particularly endophytic bacteria, remain largely unexplored. These bacteria play crucial roles in plant health, stress tolerance, and ecological interactions.

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Eight blueberry cultivars at three developmental stages were investigated for metabolite profiling, antioxidant, and anticancer activities. Cultivars- and developmental stages-variations were determined in total phenolic, flavonoid, DPPH, and FRAP antioxidant assays. The anticancer capacity was equal against A549, HepG2, and Caco-2 cancer cells, whereas the inhibition rate was dose-, incubation period-, cultivar-, and developmental stages-dependent.

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Article Synopsis
  • Three muscadine grape genotypes were analyzed for their metabolites and antioxidant properties across different berry developmental stages, identifying a total of 329 metabolites through advanced mass spectrometry techniques.
  • Principal component analysis revealed that the variations in metabolic profiles were primarily linked to the developmental stages of the berries rather than the specific genotypes.
  • A heatmap analysis highlighted 27 key biomarker compounds, with gallic acid and other compounds showing strong correlations to antioxidant activities, providing valuable insights for applications in food, pharmaceuticals, and nutraceutical fields.
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