Artificial Intelligence Powered Automated and Early Diagnosis of Acute Lymphoblastic Leukemia Cancer in Histopathological Images: A Robust SqueezeNet-Enhanced Machine Learning Framework.

The growing prevalence of acute lymphoblastic leukemia cancer worldwide underlines the critical need for early and more precise detection to counter this deadly disease. This study presents a robust SqueezeNet-enhanced machine learning framework for automatically screening and classifying histopathological images for acute lymphoblastic leukemia. This work employs a deep learning (DL)-based SqueezeNet integrated with three machine learning (ML) models including neural network (NN), logistic regression (LR), and random forest (RF) for diagnosis.

Management of Sternal Wounds, Infections, and Sternal Non-Union with Plate Fixation: Result from a Single Site Experience.

Patients with sternal wounds, infection, or non-union after cardiac surgery continue to have increased morbidity and mortality rates compared with those without sternal complications. Reconstructive methods have largely centered on soft tissue approaches, including muscle or omental flaps, which result in functional loss. Some data show early positive advantages using sternal rigid plate fixation (SRPF), however, it is debated in the setting of active infection.

A Novel Treatment for Malignant Cough Syncope.

Cough Syncope, a form of Neurocardiogenic Syncope, occurs immediately after coughing due to to arterial baroreflex-mediated vasodilatation. Cough syncope has been classically described in patients with obstructive pulmonary diseases. Pulmonary Vascular Diseases, though rare, also present with cough syncope.

An inexpensive, simple technique to improve the safety of femoral arterial puncture.

We describe a safe and inexpensive technique of avoiding femoral access site complications. Initial fluoroscopic screening of a fully inserted local anesthetic needle helps localize the anticipated arterial puncture site. Repeating fluoroscopy after guide wire insertion through the puncture needle confirms the exact puncture site in the artery.

An alternative coverage for split thickness skin graft donor site wounds.

Diabetic foot and ankle soft tissue reconstruction poses a difficult challenge to the treating surgeon, especially in cases associated with previous infection or amputation. Maintenance of a functional, plantigrade limb is important with regard to prevention of persistent or recurrent cutaneous compromise following diabetic limb salvage. Wound coverage by means of application of a split thickness skin graft (STSG) is a useful technique; however, donor site wounds require care during the early postoperative period, and can pose a challenge to wound healing in and of themselves.

An anatomical evaluation and surgical approach to the perioral mound in facial rejuvenation.

Background: Premature aging of the perioral soft tissues of the face is a common complaint of patients seeking facial rejuvenation, although its cause is unclear. The subcutaneous fat compartments of the face may be differentially affected by facial aging. Despite efforts to study and rejuvenate the aging periorbit, midface, and jowls, the effects of aging on the perioral mound have been less studied.

Biodegradable-polymer-based, paclitaxel-eluting Infinnium stent: 9-Month clinical and angiographic follow-up results from the SIMPLE II prospective multi-centre registry study.

Background: SIMPLE II was a multi-centre, prospective registry study aimed at investigating the safety and efficacy of the Infinnium (Sahajanand Medical Technologies Pvt. Ltd, India) paclitaxel-eluting stent for the treatment of single de novo lesions in the native coronary arteries.

Methods: One hundred and three patients with symptomatic coronary artery disease were treated for single de novo native coronary artery lesions using the Infinnium stent (paclitaxel concentration 1.

Instant percutaneous closure of patent foramen ovale in patients with acute myocardial infarction and normal coronary arteries.

Two young women with angiographically normal coronary arteries suffered an acute myocardial infarction. Both were found to have a patent foramen ovale (PFO), the likely pathway of a paradoxical embolus causing the infarction. The PFOs were diagnosed and closed percutaneously with an Amplatzer PFO Occluder during the emergency coronary angiography.

Left heart bypass in the pig with a centrifugal pump using cannulae prepared for percutaneous placement.

A rapid and efficient circulatory support system may save a patient in cardiogenic shock. Left heart bypass with percutaneous and trans-septal placement of the aspiration cannula simplifies the circuit and eliminates the need for an oxygenator. In this pre-clinical study we assessed left heart bypass support with a centrifugal pump using new cannulae prepared for percutaneous placement (14 F arterial catheter and 16 F left atrial aspiration line) in 5 anaesthetized pigs.

Effect of pre-treatment with transdermal glyceryl trinitrate on myocardial ischaemia during coronary angioplasty.

Objective: In the light of the reported inconsistent anti-ischaemic and antianginal effects of transdermal glyceryl trinitrate, its efficacy and influence on the effects of intracoronary glyceryl trinitrate were examined during coronary angioplasty, which provides a model of controlled, reversible ischaemia.

Design: Double blind, randomised study of the effect of transdermal and intracoronary glyceryl trinitrate on ischaemia during coronary angioplasty.

Patients: 40 patients with isolated severe stenosis of the left anterior descending coronary artery.

Use of the reversed button device to treat an atrial septal aneurysm associated with a patent foramen ovale.

An atrial septal aneurysm may be associated with a patent foramen ovale. When paradoxical emboli result, the shunt must be closed and the atrial septal aneurysm excised. A reversed buttoned occluder device was successfully used for the transcatheter treatment of this condition.

Preharvest aflatoxin contamination of groundnuts subjected to terminal drought stress in postrainy season.

Groundnuts grown in the postrainy season under terminal drought stress imposed by withholding irrigation, or under a water-deficit gradient created by line-source sprinkler irrigation, were examined for preharvest aflatoxin contamination. High levels of aflatoxin B1 were found in damaged seeds in both situations. When grown under continuous drought-stress, toxin levels in damaged seed samples ranged from 1480 to 2467 [Symbol: see text]g/kg in the 1990/91, and 1.

Coronary stenting without anticoagulation.

Stents are useful bail-out devices in coronary angioplasty. They are also used electively for situations associated with poor angioplasty results (e.g.

Stenting with the half (disarticulated) Palmaz-Schatz stent.

A total of 110 half (disarticulated) Palmaz-Schatz coronary stents were implanted in 102 patients. Procedural success rate was 98%. Elective stenting was performed in five patients.

Use of half (disarticulated) Palmaz-Schatz stents for thrombus-containing coronary lesions.

Coronary stenoses associated with thrombus can lead to poor angioplasty results and increased procedural complications. Stenting in the presence of thrombus is associated with an increased risk of stent thrombosis. We report eight patients in whom half a Palmaz-Schatz stent was implanted for inadequate angioplasty results owing to thrombus.

Coronary angioplasty in the young: procedural results and late outcome.

Procedural outcome of coronary angioplasty in 89 patients < or = 40 years was compared to an older group of 1,916 patients > 40 years. Young patients were more often male (98% vs. 81%), smokers (89% vs.

Coronary angioplasty for isolated non-dominant left circumflex coronary artery disease.

The study describes the clinical findings and results of coronary balloon angioplasty in 134 patients with non-dominant left circumflex coronary artery disease. The immediate angiographic success rate was 97% versus 95% for left anterior descending (P = NS), and 90% for right coronary lesions (P < 0.002).

Interventional cardiology: state of the art.

Since the advent of percutaneous transluminal coronary angioplasty (PCTA) in 1977, a new breed of cardiologists was born "Interventional Cardiologists". To date, a wide range of new interventions have been developed including percutaneous closure of atrial septal defects and balloon dilatation of the pulmonary valve and mitral valvuloplasty among others. In 1994, the final position of interventional cardiology is not fully defined but indicates what can be expected in the near future.

Coronary angioplasty through 4 French diagnostic catheters.

In 50 consecutive patients subjected to coronary angioplasty immediately following a 4 French (F) diagnostic study, the technical feasibility and economical aspects of angioplasty through 4F catheters of 54 lesions were assessed. The patients were selected, but multiple, eccentric, and long lesions were not a priori excluded. 4F diagnostic catheters (Cordis), and fixed-wire dilatation catheters (Ace, Scimed) were used in all cases.

Balloon recanalisation of a chronically occluded left internal mammary artery graft.

A patient in whom balloon recanalisation of a chronically occluded left internal mammary artery graft was successful is described. A Magnum-Magnarail system was used, and a four month follow up showed no restenosis.

Conventional coronary angioplasty.

Coronary angioplasty has come a long way since its inception 16 years ago. Although several new devices have shown promise, none, with the exception of the stent, has significantly changed results, and the "simple" balloon remains the backbone of coronary angioplasty. Increased operator experience and advanced guidewire and balloon technology have expanded indications for the procedure to include multivessel angioplasty, angioplasty of chronic occlusions and grafts, angioplasty in the setting of acute myocardial infarction, and supported, high-risk angioplasty.