Publications by authors named "Megumi Umehara"
Article Synopsis
- Repeated Waon therapy, using a far infrared-ray sauna, enhances cardiac function and vascular health in patients with chronic heart failure and COPD.
- In a study of 13 COPD patients, four weeks of daily Waon therapy improved exercise tolerance and quality of life, as indicated by significant increases in exercise time and scores on the St. George's Respiratory Questionnaire.
- While resting pulmonary hypertension (PH) showed no significant change, exercise-induced PH significantly decreased, demonstrating the potential benefits of Waon therapy without any observed adverse effects.
Background: Gefitinib (Iressa, ZD1839) is a selective epidermal growth factor receptor tyrosine kinase inhibitor. E2F-1 is a critical determinant in cell cycle. Growth signals up-regulate telomerase activity.
View Article and Find Full Text PDFObjective: We examined the significance of human T-cell lymphotropic virus type I (HTLV-I) Tax protein-induced resistance to anticancer drugs and the relationship between Tax and multidrug resistance proteins.
Materials And Methods: S1T cell, a leukemic non-Tax-producing T-cell clone established from an adult T-cell leukemia (ATL) patient, S1TcTax05 and S1TcTax10 clones, transfected with Tax stably expressing cDNA, and S1Tneo, transfected with a neomycin-resistant gene, were examined for Tax-related anticancer drug resistance. Resistance of those cells to the anticancer drugs doxorubicin, etoposide, cisplatin, and vindesine was tested with the MTT method.