Evaluation of factors related to overdose in patients with impaired consciousness who are transported by emergency medical services: an age-specific research.

Background: Drug overdose accounts for most of the admissions to the emergency department. Prescription drugs, most of which are psychotropic medications, are often misused for drug overdose. The purpose of this study was to investigate the association between overdose in patients transported with disorders of consciousness and psychotropic medications administered prior to transport, so as to enable quick differentiation of drug overdose patients from patients with disorders of consciousness.

[Case of thoracoabdominal stent graft with postoperative paralysis which showed dramatic recovery after re-institution of spinal drainage].

A 62-year-old man underwent stent graft insertion for thoracoabdominal aneurysm. We inserted a spinal drainage catheter at L3-4 and started drainage at 10 cmH2O at the beginning of surgery. Intravenous naloxone was started from the beginning of the operation.

Synthesis and DNA cleaving activity of water-soluble non-conjugated thienyl tetraynes.

Water-soluble non-conjugated thienyl tetraynes (3-6) were synthesized and their DNA cleaving activity was evaluated using electrophoresis, atomic force microscopy (AFM) and Escherichia coli (E. coli) transformation techniques. The amino-functionalized compound 4 was shown to possess an activity to cleave plasmid DNA by both electrophoresis and E.