Publications by authors named "Megumi Shinji"

Background: The practice patterns of exercise restrictions for patients with chronic kidney disease have not been adequately evaluated yet; thus, we examined them using a cross-sectional design and explored the factors related with those restrictions.

Methods: The Chronic Kidney Disease Japan Cohort study was a multicentre cohort study of Japanese patients (age 20-75 years) living in Japan. We used the information in the questionnaire on the restriction of physical activities offered by physicians to the patients during enrolment.

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Article Synopsis
  • The study aimed to compare the effects of sitagliptin and glimepiride on early-phase insulin secretion in Japanese patients with type 2 diabetes over 52 weeks.*
  • A total of 171 patients were randomly assigned to either treatment group, and results showed that those on sitagliptin had a significantly higher insulinogenic index and better glucose control during tests compared to those on glimepiride.*
  • Overall, sitagliptin was more effective in improving insulin secretion without changing body weight or causing significant hypoglycemia, indicating it may be a preferable treatment option for managing type 2 diabetes in this population.*
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To investigate whether the health-related quality of life (HRQOL) of patients switching from tamoxifen to anastrozole in a randomized trial is identical to that of those who continued tamoxifen after 1-4 years of adjuvant tamoxifen in Japanese postmenopausal breast cancer patients. Eligible patients for the randomized trial, the National Surgical Adjuvant Study of Breast Cancer 03, were recurrence-free postmenopausal women who had received definitive surgery for primary breast cancer with positive hormone receptor(s), and had been taking tamoxifen for 1-4 years postoperatively. They were randomly assigned to continue tamoxifen or to switch to anastrozole for a total duration of five years.

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Purpose: To evaluate linguistic validity of the Japanese version of International Prostate Symptom Score (IPSS) and BPH Impact Index (BII).

Methods: The translation was performed through multi-step procedure. Forward translation was created through the discussion by 5 urologists, 2 Japanese translators and 1 nurse on independent translations of the discussants and the translation published in the Guideline in Japan.

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