Combination of a Topical Anti-Inflammatory Drug and a Moisturizer, Both with a Lamellar Structure Containing Synthetic Pseudo-Ceramides, for the Treatment of Patients with Mild-to-Moderate Atopic Dermatitis.

Purpose: Atopic dermatitis is characterized by chronic inflammation and dryness accompanied by severe itching. The combined use of moisturizers and topical anti-inflammatory drugs is essential for alleviating atopic dermatitis. We have developed a topical anti-inflammatory drug with a steroid and a moisturizer with heparinoid, both in lamellar structure-based formulations containing synthetic pseudo-ceramides.

Translation and validation of the Japanese version of the Birth Satisfaction Scale-Revised.

Aim: This study aimed to develop a Japanese version of the Birth Satisfaction Scale-Revised and evaluate its reliability and validity.

Methods: After translating the Birth Satisfaction Scale-Revised into Japanese, we conducted an Internet-based cross-sectional study with 445 Japanese-speaking women within 2 months of childbirth. Of these, 98 participated in the retest 1 month later.

Efficacy of Heparinoid Cream Containing Pseudo-Ceramide for Remission of Atopic Dermatitis.

Purpose: Atopic dermatitis (AD) is characterized by chronic inflammation, which frequently recurs, is exacerbated, and enters remission. A maintenance remission period is important for AD patients. We developed a formulation for use during AD remission, containing heparinoid and pseudo-ceramide that forms a lamellar structure.

Prenatal diagnosis of persistent left and absent right superior vena cava.

We report a case of persistent left superior vena cava (LSVC) with absent right superior vena cava (RSVC) diagnosed prenatally. At 27 weeks' gestation, routine fetal ultrasonography showed an abnormal four-chamber view. Fetal echocardiography revealed a markedly enlarged coronary sinus in the four-chamber view.

Steroid pulse therapy for Kawasaki disease unresponsive to additional immunoglobulin therapy.

Background: The optimal management of Kawasaki disease (KD) unresponsive to intravenous immunoglobulin (IVIG) therapy remains unclear.

Objective: To prospectively evaluate the efficacy and safety of intravenous methylprednisolone pulse (IVMP) therapy in KD cases unresponsive to additional IVIG.

Methods: KD patients who initially received IVIG (2 g/kg/24 h) and acetylsalicylic acid within nine days after disease onset were studied.

Early parenting program as intervention strategy for emotional distress in first-time mothers: a propensity score analysis.

The purpose of this study is to evaluate the effectiveness of a single session intervention designed to reduce emotional distress in first-time mothers. We held a parenting class for first-time mothers who had given birth at a university hospital in Tokyo, Japan. The program of the class consists of lectures on infant care and group discussion, which is a common form of intervention in Japan.

Life-threatening atrial tachycardia after the Senning operation in a patient with transposition of the great arteries.

Atrial tachycardia (AT) is recognized as a risk factor of sudden death (SD) in patients with transposition of the great arteries (TGA) after atrial switch operation. A 20-year-old man with TGA who had undergone a Senning operation experienced a near-miss SD event 1 day after appearance of AT. He was successfully resuscitated by electrical defibrillation for documented ventricular fibrillation.

Antenatal three-dimensional sonographic features of Roberts syndrome.

Introduction: We present a fetus whose characteristics most likely represent Roberts syndrome.

Case Report: Prenatal diagnosis at 21 weeks and 1 day age of gestation was made employing conventional two-dimensional (2D) sonography, showing shortened upper and lower extremities. An umbilical cord cyst was also noted.

A trial product of a new safety belt for a wheelchair user and its evaluation based on the actual investigation of fall accidents related to wheelchairs in a hospital.

Old-aged patients, especially when they cannot keep stable sitting postures on wheelchairs, may get hurts seriously by falls. Preventing fall accidents is one of the most important subjects for keeping ADL of old-aged persons. We investigated the fall accidents related to from wheelchairs that occurred in a hospital (Asao General Hospital of Rehabilitation), and tried to make a new type of safety belts for old-aged wheelchair users based on the investigation.

The basic problems of bed-fence-covers in hospitals for preventing accidents based on the investigation into the actual conditions: for developing the safer bed-fence-cover for elderly patients.

The basic problems of bed-fence-covers in hospitals were listed for preventing relevant accidents based on the investigation into actual conditions in a hospital in Kawasaki City. There were many elderly aged patients with dementia, higher brain dysfunction or psychosis in the hospital. They sometimes fell into the gaps of bed-fences, resulting in serious accidents.

Formation of lysophosphatidic acid, a wound-healing lipid, during digestion of cabbage leaves.

Lysophosphatidic acid (LPA) is a lipid mediator that plays a role in the process of wound healing in animal tissues, including the digestive tract. We determined LPA in several foodstuffs, and found that cabbage leaves were the richest source of LPA. We also found that, at 22 and 195 nmol/g (wet weight), LPA and phosphatidic acid (PA) were respectively formed during mastication of raw cabbage leaves and that the resulting PA was converted to LPA by pancreatic phospholipase A(2).

Causal model structure analysis of emotional unrest in first time mothers faced with persistent infant crying 6-7 weeks postpartum.

Unlabelled: First time mothers faced with a continuously crying infant, who do not know how to stop their child from crying, are at risk of developing anxiety and other types of Emotional Unrest. Because continuous Emotional Unrest may lead to an emotional crisis, it is important for healthcare providers to understand causal factors associated with Emotional Unrest among first time mothers faced with a persistently crying infant 6-7 weeks postpartum.

Methods: A cross-sectional survey was carried out on a study population of 217 first time mothers with infants aged 6-7 weeks.

[Methylprednisolone pulse therapy in Kawasaki disease].

A role of intravenous methylprednisolone pulse (IVMP) therapy has not been established for Kawasaki disease (KD) patients unresponsive to initial intravenous immunoglobulin (IVIG) therapy. We conducted a control study in 22 KD patients unresponsive to initial IVIG to compare IVMP with additional IVIG. IVMP induced faster but temporary resolution of fever and more adverse effects such as bradycardia.

Changes in breast skin temperature during the course of breastfeeding.

Breast skin temperature was measured during breastfeeding in 11 mothers on a total of 47 occasions, using a Coretemp CM-210 (Terumo Corp, Tokyo, Japan), to examine the changes of breast skin temperature during the course of breastfeeding. In both breasts, the breast skin temperature was significantly higher than the baseline skin temperature from the beginning of suckling up to 5 minutes after completion of suckling, and the mean breast skin temperature before breastfeeding between 4 days and 8 weeks postpartum was significantly higher than that on the first 1 to 2 days postpartum. These results show that the breast skin temperature increases between the first 1 to 2 days and 4 to 5 days postpartum and that breast skin temperature remains high during suckling and up to 5 minutes after the completion of suckling.