Synopsis of recent research by authors named "Meghna Wagley"
Meghna Wagley's research primarily focuses on the epigenetic mechanisms regulating chromatin architecture, particularly how linker histone (LH) density influences chromatin transitions and overall genomic organization.
In her 2022 study, she utilizes mesoscale chromatin modeling to reveal how varying LH densities induce significant structural changes in chromatin, highlighting the importance of linker length and binding dynamics in this process.
Her earlier work from 2021 investigates the clustering behavior of nucleosomes, introducing the concept of "clutches" that enhances our understanding of chromatin regulation during critical biological processes like cell differentiation.
