Divergence Between Clinician and Patient Perspectives on Polygenic Embryo Screening: A Qualitative Study.

Objective: To explore and compare the perspectives of clinicians and patients on polygenic embryo screening.

Design: Qualitative.

Subjects: Fifty-three participants: 27 reproductive endocrinology and infertility specialists and 26 patients currently undergoing in vitro fertilization or had done so within the last five years.

Tuberculosis case notification by registered private medical practitioners in Kolkata: A mixed-methods study.

Background: Under-notification of tuberculosis (TB) cases remains a persistent problem that impedes accurate estimation of the disease burden. India's private health sector contributes to only one-fourth of the total TB notifications.

Objectives: The present study was conducted among registered private practitioners in Kolkata to assess their knowledge, attitude and practice on TB notification, to find the socio-demographic and work-related factors associated with it, to identify the barriers faced by them in notifying TB cases and to elicit suggested solutions in overcoming these barriers.

Medicalizing risk: How experts and consumers manage uncertainty in genetic health testing.

Given increased prevalence of direct-to-consumer (DTC) genetic health tests in recent years, this paper delves into discourses among researchers at professional genomics conferences and lay DTC genetic test users on popular discussion website Reddit to understand the contested value of genetic knowledge and its direct implications for health management. Harnessing ethnographic observations at five conferences and a text -analysis of 52 Reddit threads, we find both experts and lay patient-consumers navigate their own versions of "productive uncertainty." Experts develop genetic technologies to legitimize unsettled genomics as medical knowledge and mobilize resources and products, while lay patient-consumers turn to Internet forums to gain clarity on knowledge gaps that help better manage their genetic risk states.

Clinical profile and predictors of therapeutic outcome with azithromycin in pediatric scrub typhus: A study from Eastern India.

In this prospective study, children from 1-month to 12-years, admitted with positive IgM ELISA testing for scrub typhus, were enrolled over 1-year and administered an empirical single dose of azithromycin (10 mg/kg). All 189 (median age 4.84-years) children had fever with median duration of 8 days at admission.

The Management of Unequal Patient Status in Fertility Medicine: Donors' and Intended Parents' Experiences of Participatory and Imposed Enrollment.

This paper explores the micro-dynamics of medicalization and unequal patient statuses across donors and intended parents in assisted fertility practices. Based on twelve months of fieldwork in a fertility clinic, including direct observations of 108 patient-medical expert consultations and interviews with donors, I develop an "epistemic-orientation (EO) continuum" to examine the emergence and differing consequences of unequal patient status. Patients who experience practices closer to the "participatory" epistemic orientation end of the continuum enjoy joint decision-making, personal and emotional recognition, and incorporation of their personal values in interactions with medical experts in the clinic.