Publications by authors named "Meghan M Pantalia"
In , ~150 neurons expressing molecular clock proteins regulate circadian behavior. Sixteen of these neurons secrete the neuropeptide Pdf and have been called 'master pacemakers' because they are essential for circadian rhythms. A subset of Pdf neurons (the morning oscillator) regulates morning activity and communicates with other non-Pdf neurons, including a subset called the evening oscillator.
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- Fragile X syndrome is the leading known genetic cause of autism and is linked to the loss of the FMR1 protein, which is crucial for RNA binding.
- Research indicates that individuals with Fragile X syndrome have immune system defects, showing increased susceptibility to infections and reduced ability to clear bacteria by immune cells.
- The study reveals that FMR1 is important for the functioning of immune cells in both body and brain, impacting processes like neuronal clearance after injury and brain development essential for learning and memory.