Publications by authors named "Meghan A Callahan"
J Clin Immunol
April 2024
Article Synopsis
- The CDC and ACIP endorse COVID-19 vaccination for patients with inborn errors of immunity (IEI), but there's limited knowledge on its safety and impact on infection severity in these patients.
- A study involving a registry of 1,245 IEI patients across 24 countries was conducted to gather data on vaccination frequency, safety, and effectiveness, revealing that 64.7% were vaccinated, primarily with mRNA vaccines.
- Results showed that vaccinated patients had significantly lower hospitalization and ICU admission rates when infected with COVID-19, indicating that vaccination is both safe and effective in reducing the severity of the disease in IEI patients.
J Osteopath Med
April 2023
Article Synopsis
- Structural skeletal abnormalities are commonly observed in primary immunodeficient (PID) patients, suggesting a potential link between these irregularities and overall immune function.
- A case study was conducted on a patient with a specific genetic mutation (PIK3R1) who exhibited various skeletal issues, coupled with a detailed osteopathic structural clinical examination (OSCE) to evaluate somatic dysfunctions.
- A literature review highlighted that multiple PIDs exhibit associated structural abnormalities, indicating that these irregularities may further complicate the immune system's functionality in affected individuals.
