Publications by authors named "Megha Bhat Agni"
Article Synopsis
- Nutrition significantly impacts the health of both mothers and their offspring, particularly during critical periods like gestation and lactation, where undernutrition can lead to metabolic disorders such as obesity and cardiovascular diseases.
- A study evaluated the effects of maternal undernutrition on the plasma metabolic profiles of mothers, revealing increased levels of harmful lipids and dysregulated pathways related to cholesterol and hormone metabolism.
- Supplementation with astaxanthin and DHA showed promise in mitigating these negative effects by positively influencing various lipid metabolism pathways, potentially improving health outcomes for both mothers and their offspring.
Maternal nutrition was recognized as a significant part of brain growth and maturation in most mammalian species. Timely intervention with suitable nutraceuticals would provide long-term health benefits. We aim to unravel the molecular mechanisms of perinatal undernutrition-induced impairments in cognition and synaptic plasticity, employing animal model based on dietary nutraceutical supplementation.
View Article and Find Full Text PDFPerinatal undernutrition stress predisposes several disorders in adult life, which could be programed using nutraceuticals. However, the effect of perinatal undernutrition stress on orexin peptides, brain lipids, and its amelioration by a potent antioxidant (Astaxanthin) needs exploration. The present study focussed on the effect of perinatal undernutrition stress on brain fatty acid levels, Orexin peptides A and B, and its amelioration by Astaxanthin.
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