Publications by authors named "Meggan M Zsemlye"
Article Synopsis
- The study investigates how elastic light scattering measurements can help identify cervical intraepithelial neoplasias (CIN) and cancers in women during colposcopy procedures, focusing on the impact of factors like menstrual status on results.
- A fiber optic probe collected spectroscopic data from 151 patients, which was then compared to histopathology results to develop a classification system, revealing significant influences from age, menopausal status, and menstrual cycle timing.
- The findings indicate that, when adjusted for these factors, elastic light scattering spectroscopy could effectively assist in real-time cervical tissue diagnosis, with current sensitivity and specificity rates suggesting potential uses in guiding biopsies and enhancing "see and treat" approaches.
A noninvasive optical diagnostic system for detection of cancerous and precancerous lesions of the cervix was evaluated in vivo. The optical system included a fiber-optic probe designed to measure polarized and unpolarized light transport properties of a small volume of tissue. An algorithm for diagnosing tissue based on the optical measurements was developed that used four optical properties, three of which were related to light scattering properties and the fourth of which was related to hemoglobin concentration.
View Article and Find Full Text PDFWomen look to their internists and other primary care physicians to provide preventive health care. Periodic Pap tests are as much a part of a woman's ongoing health care as periodic lipid assessments, mammograms, screening for colon cancer, or any of the other recommended screening assessments. This article provides primary care physicians with the information needed to perform Pap tests at the appropriate intervals, or if not set up to do Pap tests themselves, to make the appropriate referrals.
View Article and Find Full Text PDFObjective: To examine the utility of in vivo elastic light scattering measurements to diagnose high grade squamous interepithelial lesions (HSIL) of the cervix.
Methods: A newly developed fiber optic probe was used to measure light transport in the cervical epithelium of 36 patients undergoing standard colposcopy. Both unpolarized and polarized light transport were measured in the visible and near-infrared.