Publications by authors named "Megan Von Isenburg"
Article Synopsis
- - The study addresses disparities in neurosurgical care globally and examines how collaborations have shifted from traditional mission trips to partnerships, analyzing the impact of research funding on these collaborations using a graph theoretical approach.
- - A bibliometric search found 307 neurosurgical articles published from 1985 to 2020, revealing that co-authorship rates between high-income and low- or middle-income countries have increased significantly, especially after 2015, with LMIC-LMIC partnerships rising at a faster pace than others.
- - Research funding plays a crucial role in fostering collaborations, as funding from charitable organizations and government grants was linked to increased co-authorship between LMIC and HIC authors, while most LMIC-LMIC co-authorship
Objectives: Precision medicine is data-driven health care tailored to individual patients based on their unique attributes, including biologic profiles, disease expressions, local environments, and socioeconomic conditions. Emergency medicine (EM) has been peripheral to the precision medicine discourse, lacking both a unified definition of precision medicine and a clear research agenda. We convened a national consensus conference to build a shared mental model and develop a research agenda for precision EM.
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- Neurotrauma is a major health issue in Nigeria, leading to high rates of illness and death, prompting a systematic review to provide valuable nationwide data.
- The study analyzed data from 45,763 patients across 254 articles, revealing a predominance of traumatic brain injuries primarily caused by road traffic accidents, with most patients being young males.
- Despite 63.7% of traumatic brain injury patients showing favorable outcomes, only 20.9% of those with spinal injuries fared similarly, highlighting the critical need for focused interventions in managing neurotrauma in the country.
Article Synopsis
- The study reviews the development and challenges of vascular neurosurgery in Nigeria by analyzing literature from 1962 to 2021.
- A total of 56 articles were evaluated, involving 3203 patients, with a moderate to high risk of bias, indicating that most studies were retrospective cohort studies and case reports.
- The findings showed that cerebrovascular accidents predominated, particularly due to trauma, with favorable outcomes reported in 48% of cases and a mortality rate of 6%, highlighting key issues in neurovascular health in Nigeria.
Objective: Spinal pathologies are prevalent in Nigeria, though epidemiological data remains sparse. This systematic review used pooled patient-level data from across the country to generate a standardized epidemiological reference.
Methods: Four research databases and gray literature sources were searched.
Article Synopsis
- * A systematic review identified 147 studies and over 5,700 patients, revealing a significant rise in the types of tumors diagnosed and the use of imaging techniques like CT and MRI.
- * The findings emphasize the need for further research to improve understanding and enhance neuro-oncologic care in Nigeria, particularly in underrepresented treatment options like chemotherapy.
Objective: Despite 6 decades of existence, neurosurgery is still in the developing stages in Nigeria. In this era of collaborative health system capacity-building in low- and middle-income countries, this article reviews past efforts and future prospects for collaborative neurosurgical development in Nigeria.
Methods: A bibliometric review of the Nigerian neurosurgical literature and data from a structured survey of Nigerian neurosurgeons and residents provided details of current local and international collaborations for neurosurgical research, service delivery, training, and capacity building.
Objective: This study aims to provide a comprehensive overview of pediatric neurosurgery in Nigeria, since 1962, by assessing epidemiological data, management strategies, and case outcomes.
Methods: A systematic bibliometric review of Nigerian neurosurgical literature was reported with the PRISMA guidelines. The Risk of Bias Assessment Tool was applied to all nonrandomized studies, and a descriptive analysis was performed for all variables.
Objective: This study investigates the scope, trends, and challenges of neurosurgical research in Nigeria since inception of the specialty in 1962.
Methods: A bibliometric review of the neurosurgical literature from Nigeria was performed. Variables extracted included year and journal of publication, article topic, article type, research type, study design, article focus area, and limitations.
Intimate partner violence (IPV) is a global public health crisis with long-term adverse consequences for both victims and perpetrators. Patterns of violence often begin during adolescence, yet most interventions target adult relationships. A systematic review was conducted to identify correlates of IPV victimization and perpetration among adolescents and young adults in sub-Saharan Africa (SSA).
View Article and Find Full Text PDFBackground: The onset of the COVID-19 pandemic and the concurrent development of vaccines offered a rare and somewhat unprecedented opportunity to study antivaccination behavior as it formed over time via the use of archived versions of websites.
Objective: This study aims to assess how existing antivaccination websites modified their content to address COVID-19 vaccines and pandemic restrictions.
Methods: Using a preexisting collection of 25 antivaccination websites curated by the IvyPlus Web Collection Program prior to the pandemic and crawled every 6 months via Archive-It, we conducted a content analysis to see how these websites acknowledged or ignored COVID-19 vaccines and pandemic restrictions.
Background: Emergency medical services (EMS) often serve as the first medical contact for ill or injured patients, representing a critical access point to the health care delivery continuum. While a growing body of literature suggests inequities in care within hospitals and emergency departments, limited research has comprehensively explored disparities related to patient demographic characteristics in prehospital care.
Objective: We aimed to summarize the existing literature on disparities in prehospital care delivery for patients identifying as members of an underrepresented race, ethnicity, sex, gender, or sexual orientation group.
Objective: Emergency medical services (EMS) workforce demographics in the United States do not reflect the diversity of the population served. Despite some efforts by professional organizations to create a more representative workforce, little has changed in the last decade. This scoping review aims to summarize existing literature on the demographic composition, recruitment, retention, and workplace experience of underrepresented groups within EMS.
View Article and Find Full Text PDFBackground: The high unmet neurosurgical burden in low- and middle-income countries has necessitated multiple global neurosurgical collaborations. We identified these collaborations and their peer-reviewed journal publications and evaluated them using a modified version of the Framework for Assessment of InteRNational Surgical Success (FAIRNeSS).
Methods: A systematic literature review yielded 265 articles describing neurosurgery-focused collaborations.
Background: Here, we evaluate the evolution and growth of global neurosurgery publications over time, further focusing on the contributions and impact of authors in low- and middle-income countries (LMICs).
Methods: In this systematic bibliometric analysis, we conducted a two-stage blinded screening process of global neurosurgery publications from 5 databases from inception through July 2021. Articles involving multi-national/multi-institutional research collaborations, detailing any area of global neurosurgery collaboration, or influencing global neurosurgery practice were included.
Objective: Africa contributes significantly to the global neurosurgical disease burden but has only 1% of the neurosurgery workforce. This study appraises the neurosurgical workforce and training capacity in Africa and projects the workforce capacity by 2030.
Methods: The authors conducted a systematic review of the online literature on neurosurgical workforce and training in Africa obtained from three journal databases (PubMed, Embase, and African Index Medicus), as well as from a gray literature search, between September and December 2020.
Background: This survey of COVID-19 interventional studies encompasses, and expands upon, a previous publication [1] examining individual participant level data (IPD) sharing intentions for COVID-related trials and publications prior to June 30, 2020.
Methods: Replicating our inclusion criteria from the original survey, we evaluated a larger dataset of 2759 trials and 281 publications in this follow-up survey for willingness to share IPD and studied if sharing sentiment has evolved since the beginning of the pandemic.
Results: We found that 18 months into the pandemic, data sharing intentions remained static at 15% for trials registered through ClinicalTrials.
COVID-19-associated psychosis: A systematic review of case reports.
Gen Hosp Psychiatry
December 2021
Objectives: To describe the comorbidities, presentations, and outcomes of adults with incident psychosis and a history of COVID-19.
Methods: We completed a descriptive systematic review of case reports according to PRISMA guidelines, including cases of adult patients with incident psychosis and antecedent or concurrent COVID-19. We extracted patient demographics, comorbidities, clinical course, and outcomes, and assessed cases for quality using a standardized tool.
Objective: The purpose of this scoping review is to evaluate the extent of library or librarian involvement in informatics education in the health domain.
Methods: We searched eight databases from their inception to 2019 for reports of informatics educational activities for health professionals or health professions students that involved library staff or resources. Two reviewers independently screened all titles/abstracts (n=2,196) and resolved inclusion decisions by consensus.
Introduction: Addressing the intersection between mental health and HIV is critical for the wellbeing of persons living with HIV (PLWH). This systematic review synthesized the literature on mental health interventions for PLWH in low- and middle-income countries (LMICs) to determine intervention components and explore their relationship with intervention effectiveness.
Methods: We included only controlled clinical trials of interventions aiming to improve the mental health of PLWH.
Background: Emergency Medical Services (EMS) systems exist to reduce death and disability from life-threatening medical emergencies. Less than 9% of the African population is serviced by an emergency medical services transportation system, and nearly two-thirds of African countries do not have any known EMS system in place. One of the leading reasons for EMS utilization in Africa is for obstetric emergencies.
View Article and Find Full Text PDFBackground: Nearly 90% of deaths due to cervical cancer occur in low- and middle-income countries (LMICs). In recent years, many digital health strategies have been implemented in LMICs to ameliorate patient-, provider-, and health system-level challenges in cervical cancer control. However, there are limited efforts to systematically review the effectiveness and current landscape of digital health strategies for cervical cancer control in LMICs.
View Article and Find Full Text PDFThere is an urgent need to understand the risk of viral transmission during nebulizer treatment of patients with coronavirus disease 2019 (COVID-19). To assess the risk of transmitting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), SARS, Middle East respiratory syndrome (MERS), and influenza with administration of drugs via nebulizer. We searched multiple electronic databases, including PubMed, China National Knowledge Infrastructure, Wanfang, preprint databases, and clinicaltrials.
View Article and Find Full Text PDFBackground: The sharing of individual participant-level data from COVID-19 trials would allow re-use and secondary analysis that can help accelerate the identification of effective treatments. The sharing of trial data is not the norm, but the unprecedented pandemic caused by SARS-CoV-2 may serve as an impetus for greater data sharing. We sought to assess the data sharing intentions of interventional COVID-19 trials as declared in trial registrations and publications.
View Article and Find Full Text PDFInjuries are a leading cause of death and disability among children. Numerous injury prevention strategies have been successful in high-income countries, but the majority of unintentional injuries happen to children living in low- and middle-income countries (LMICs). This project aims to delineate the childhood injury prevention initiatives in LMICs.
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