Publications by authors named "Megan Traynham"
Article Synopsis
- Morphine is effective for pain relief in horses, but intravenous (IV) use can cause unwanted side effects like neuroexcitation and gastrointestinal issues.
- Oral administration of morphine yields similar pain-relief potential through the metabolite M6G without the negative effects of IV administration.
- The study found that oral morphine doses provided effective pain relief comparable to IV morphine while causing less excitation and gastrointestinal disturbances, indicating the need for further research.
Butorphanol is commonly administered, both by the intravenous and intramuscular routes, to racehorses to facilitate handling for diagnostic procedures. As the administration of butorphanol for therapeutic purposes is considered appropriate, in order to avoid inadvertent positive drug tests, a thorough understanding of the pharmacokinetics of this drug is necessary. In the current study, 12, exercised Thoroughbred horses were administered a single intramuscular dose of 0.
View Article and Find Full Text PDFThe metabolism and pharmacokinetics of intravenous (i.v.) morphine in the horse have been described; however, administration of therapeutic doses has also been associated with neuroexcitation and adverse gastrointestinal effects.
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