Publications by authors named "Megan R Brady"

Article Synopsis
  • Spirochete bacteria swim using a unique method that involves undulating movements powered by supercoiled 'endoflagella' that wrap around their bodies.
  • Researchers studied the structure of these flagellar filaments using advanced techniques like cryo-electron tomography and X-ray crystallography.
  • Their findings revealed that the filaments are covered by a complex, asymmetric sheath layer, which differs from the simpler structures seen in other bacteria, helping to explain the special supercoiling necessary for the spirochete's motility.
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To understand the roles ion pairs play in stabilizing coiled coils, we determined nuclear magnetic resonance structures of GCN4p at three pH values. At pH 6.6, all acidic residues are fully charged; at pH 4.

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